Articles with "boswellic acid" as a keyword



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Inhibitory effect of 11-carbonyl-beta-boswellic acid on non-small cell lung cancer H446 cells.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.06.137

Abstract: BACKGROUND The anti-lung tumor potential of 11-carbonyl-β-boswellic acid was investigated. MATERIALS & METHODS The inhibitory effects of 11-carbonyl-β-boswellic acid on non-small cell lung cancer (NSCLC) was assessed by proliferation, apoptosis, cell cycle and molecular mechanisms… read more here.

Keywords: carbonyl boswellic; cell; boswellic acid; h446 cells ... See more keywords
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The effects of acetyl-11-keto-β-boswellic acid on brain cytokines and memory impairment induced by lipopolysaccharide in rats.

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Published in 2020 at "Cytokine"

DOI: 10.1016/j.cyto.2020.155107

Abstract: The therapeutic effects of the olibanum, the resin of Boswellia serrata on inflammatory diseases have been reported. There are more than 200 active ingredients in this resin including acetyl-11-keto-β-boswellic acid (AKBA). We proposed that AKBA… read more here.

Keywords: keto boswellic; acetyl keto; boswellic acid; memory impairment ... See more keywords
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β-Boswellic Acid Suppresses Breast Precancerous Lesions via GLUT1 Targeting-Mediated Glycolysis Inhibition and AMPK Pathway Activation

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.896904

Abstract: Breast carcinoma is a multistep progressive disease. Precancerous prevention seems to be crucial. β-Boswellic acid (β-BA), the main component of the folk medicine Boswellia serrata (B. serrata), has been reported to be effective in various… read more here.

Keywords: glut1; ampk pathway; glycolysis; boswellic acid ... See more keywords
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β Boswellic Acid Blocks Articular Innate Immune Responses: An In Silico and In Vitro Approach to Traditional Medicine

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Published in 2023 at "Antioxidants"

DOI: 10.3390/antiox12020371

Abstract: Osteoarthritis (OA) is hallmarked as a silent progressive rheumatic disease of the whole joint. The accumulation of inflammatory and catabolic factors such as IL6, TNFα, and COX2 drives the OA pathophysiology into cartilage degradation, synovia… read more here.

Keywords: immune responses; acid blocks; boswellic acid; innate immune ... See more keywords
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Nrf2/HO-1 Signaling Stimulation through Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) Provides Neuroprotection in Ethidium Bromide-Induced Experimental Model of Multiple Sclerosis

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Published in 2022 at "Genes"

DOI: 10.3390/genes13081324

Abstract: Multiple sclerosis (MS) is a severe immune-mediated neurological disease characterized by neuroinflammation, demyelination, and axonal degeneration in the central nervous system (CNS). This is frequently linked to motor abnormalities and cognitive impairments. The pathophysiological hallmarks… read more here.

Keywords: acetyl keto; sclerosis; akba; brain ... See more keywords
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Evaluation of the Anti-Atopic Dermatitis Effects of α-Boswellic Acid on Tnf-α/Ifn-γ-Stimulated HaCat Cells and DNCB-Induced BALB/c Mice

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23179863

Abstract: Boswellic acids, triterpenoids derived from the genus Boswellia (Burseraceae), are known for their anti-inflammatory and anti-tumor efficacy. Atopic dermatitis is a chronic, non-infectious inflammatory skin disease. However, the effects of α-boswellic acid on atopic dermatitis… read more here.

Keywords: balb mice; tnf ifn; boswellic acid; atopic dermatitis ... See more keywords
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Protective Effect and Mechanism of Boswellic Acid and Myrrha Sesquiterpenes with Different Proportions of Compatibility on Neuroinflammation by LPS-Induced BV2 Cells Combined with Network Pharmacology

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Published in 2019 at "Molecules"

DOI: 10.3390/molecules24213946

Abstract: Frankincense and myrrha (FM), commonly used as a classical herbal pair, have a wide range of clinical applications and definite anti-inflammatory activity. However, anti-neuroinflammation effects and mechanisms are not clear. In this study, we adopted… read more here.

Keywords: boswellic acid; network; neuroinflammation; myrrha ... See more keywords
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Plant-Derived Molecules α-Boswellic Acid Acetate, Praeruptorin-A, and Salvianolic Acid-B Have Age-Related Differential Effects in Young and Senescent Human Fibroblasts In Vitro

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Published in 2019 at "Molecules"

DOI: 10.3390/molecules25010141

Abstract: Testing and screening of plant-derived molecules on normal human cells in vitro is a widely used approach for discovering their eventual health beneficial effects for human ageing and longevity. As little is known about age-associated… read more here.

Keywords: boswellic acid; age; differential effects; plant derived ... See more keywords
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11-Keto-α-Boswellic Acid, a Novel Triterpenoid from Boswellia spp. with Chemotaxonomic Potential and Antitumor Activity against Triple-Negative Breast Cancer Cells

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules26020366

Abstract: Boswellic acids, and particularly 11-keto-boswellic acids, triterpenoids derived from the genus Boswellia (Burseraceae), are known for their anti-inflammatory and potential antitumor efficacy. Although boswellic acids generally occur as α-isomers (oleanane type) and β-isomers (ursane type),… read more here.

Keywords: boswellic acids; keto boswellic; boswellic acid; potential antitumor ... See more keywords
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The Protective Effect of 11-Keto-β-Boswellic Acid against Diabetic Cardiomyopathy in Rats Entails Activation of AMPK

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Published in 2023 at "Nutrients"

DOI: 10.3390/nu15071660

Abstract: This study examined the protective effect of 11-keto-β-boswellic acid (AKBA) against streptozotocin (STZ)-induced diabetic cardiomyopathy (DC) in rats and examined the possible mechanisms of action. Male rats were divided into 5 groups (n = 8/each):… read more here.

Keywords: keto boswellic; akba; effect keto; protective effect ... See more keywords
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Analysis of Boswellic Acid Contents and Related Pharmacological Activities of Frankincense-Based Remedies That Modulate Inflammation

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Published in 2021 at "Pharmaceuticals"

DOI: 10.3390/ph14070660

Abstract: Extracts of frankincense, the gum resin of Boswellia species, have been extensively used in traditional folk medicine since ancient times and are still of great interest as promising anti-inflammatory remedies in Western countries. Despite their… read more here.

Keywords: boswellic acid; analysis boswellic; inflammation; acid contents ... See more keywords