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Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.07.012
Abstract: Crofelemer is a botanical polymeric proanthocyanidin that inhibits chloride channel activity and is used clinically for treating HIV-associated secretory diarrhea. Crofelemer lots may exhibit significant physicochemical variation due to the natural source of the raw…
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Keywords:
drug substance;
crofelemer;
drug;
model ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.789311
Abstract: Osteoarthritis (OA) is a long-term chronic arthrosis disease which is usually characterized by pain, swelling, joint stiffness, reduced range of motion, and other clinical manifestations and even results in disability in severe cases. The main…
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Keywords:
degeneration;
drug extracts;
cartilage;
botanical drug ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.855384
Abstract: Botanical drug products consist of complex phytochemical constituents that vary based on various factors that substantially produce different pharmacological activities and possible side effects. Marantodes pumilum (Blume) Kuntze (Primulaceae) is one of the most popular…
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Keywords:
authentication;
marantodes pumilum;
pumilum blume;
blume kuntze ... See more keywords