Molecular cloning and structural modelling of gamma-phospholipase A2 inhibitors from Bothrops atrox and Micrurus lemniscatus snakes.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.05.076
Abstract: Phospholipases A2 inhibitors (PLIs) produced by venomous and non-venomous snakes play essential role in this resistance. These endogenous inhibitors may be classified by their fold in PLIα, PLIβ and PLIγ. Phospholipases A2 (PLA2s) develop myonecrosis… read more here.
Keywords: gene sequences; micrurus lemniscatus; atrox micrurus; bothrops atrox ... See more keywords
Crystal structure and molecular dynamics studies of L‐amino acid oxidase from Bothrops atrox
Sign Up to like & getrecommendations! Published in 2017 at "Toxicon"
DOI: 10.1016/j.toxicon.2017.01.017
Abstract: ABSTRACT L‐amino acid oxidases (LAAOs) are dimeric flavoproteins that catalyze the deamination of L‐amino acid to &agr;‐keto acid, producing ammonia and hydrogen peroxide. In this study, we report the crystal structure and molecular dynamics simulations… read more here.
Keywords: crystal structure; amino acid; structure molecular; molecular dynamics ... See more keywords
Experimental Bothrops atrox envenomation: Efficacy of antivenom therapy and the combination of Bothrops antivenom with dexamethasone
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0005458
Abstract: Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There are discrepancies in… read more here.
Keywords: antivenom therapy; bothrops atrox; bothrops antivenom; dexamethasone ... See more keywords
Oral microbiota in healthy Bothrops atrox (Serpentes: Viperidae) and in snakes with stomatitis
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DOI: 10.21708/avb.2017.11.0.7157
Abstract: The purpose of this study was to isolate bacteria found in the oral cavity of healthy Bothrops atrox and in snakes with stomatitis. The area around the snake fang sheaths were swabbed and the samples… read more here.
Keywords: snakes stomatitis; healthy bothrops; spp; bothrops atrox ... See more keywords
Diversity of Phospholipases A2 from Bothrops atrox Snake Venom: Adaptive Advantages for Snakes Compromising Treatments for Snakebite Patients
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14080543
Abstract: The evolution of snake venoms resulted in multigene toxin families that code for structurally similar isoforms eventually harboring distinct functions. PLA2s are dominant toxins in viper venoms, and little is known about the impact of… read more here.
Keywords: snake venom; atrox snake; diversity; phospholipases bothrops ... See more keywords