Carbohydrate-independent antibiofilm effect of Bothrops jararacussu lectin BJcuL on Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2019 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2019.103745
Abstract: The antivirulence approach to fighting biofilm-based infections caused by Staphylococcus aureus is a promising therapy that has been studied extensively. Here, we compare the antibiofilm activity of a purified lectin from Bothrops jararacussu venom (BJcuL)… read more here.
Keywords: staphylococcus aureus; bjcul; effect; bothrops jararacussu ... See more keywords
Reproduction in the pitviper Bothrops jararacussu: large females increase their reproductive output while small males increase their potential to mate.
Sign Up to like & getrecommendations! Published in 2020 at "Zoology"
DOI: 10.1016/j.zool.2020.125816
Abstract: Reproductive traits vary widely within and among snake species, and are influenced by a range of factors. However, additional studies are needed on several species, especially on tropical snake faunas, to fully understand the patterns… read more here.
Keywords: increase reproductive; potential mate; size; bothrops jararacussu ... See more keywords
The allosteric activation mechanism of a phospholipase A2-like toxin from Bothrops jararacussu venom: a dynamic description
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73134-9
Abstract: The activation process of phospholipase A2-like (PLA2-like) toxins is a key step in their molecular mechanism, which involves oligomeric changes leading to the exposure of specific sites. Few studies have focused on the characterization of… read more here.
Keywords: toxin bothrops; bothrops jararacussu; phospholipase like; toxin ... See more keywords
Prospective study of a Bothrops jararacussu venom batch (Bj2015) – phospholipase A2 activity, immunogenicity, neurotoxicity, and myotoxicity parameters
Sign Up to like & getrecommendations! Published in 2019 at "Natural Product Research"
DOI: 10.1080/14786419.2018.1446010
Abstract: Abstract Bothrops jararacussu venom’s (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries… read more here.
Keywords: immunogenicity; myotoxicity; bj2015; bothrops jararacussu ... See more keywords
Photobiomodulation mitigates Bothrops jararacussu venom-induced damage in myoblast cells by enhancing myogenic factors and reducing cytokine production
Sign Up to like & getrecommendations! Published in 2024 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0012227
Abstract: Background Photobiomodulation has exhibited promise in mitigating the local effects induced by Bothrops snakebite envenoming; however, the mechanisms underlying this protection are not yet fully understood. Herein, the effectiveness of photobiomodulation effects on regenerative response… read more here.
Keywords: jararacussu venom; bothrops jararacussu; myoblast cells; myogenic factors ... See more keywords
In Silico Evaluation of Quercetin Methylated Derivatives on the Interaction with Secretory Phospholipases A2 from Crotalus durissus terrificus and Bothrops jararacussu
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16040597
Abstract: Quercetin derivatives have already shown their anti-inflammatory potential, inhibiting essential enzymes involved in this process. Among diverse pro-inflammatory toxins from snake venoms, phospholipase A2 is one of the most abundant in some species, such as… read more here.
Keywords: durissus terrificus; terrificus bothrops; crotalus durissus; quercetin ... See more keywords
BthTX-II, an Asp49 PLA2 from Bothrops jararacussu, Impairs Toxoplasma gondii Infection: In Vitro and Ex Vivo Approaches
Sign Up to like & getrecommendations! Published in 2025 at "Pharmaceuticals"
DOI: 10.3390/ph18091260
Abstract: Background/Objectives: Toxoplasma gondii, an obligate intracellular parasite, poses a major global health concern owing to its potential for congenital transmission, particularly during pregnancy. Current pharmacological treatments, including spiramycin and pyrimethamine, exhibit limitations in both efficacy… read more here.
Keywords: toxoplasma gondii; bothrops jararacussu; asp49 pla2; proliferation ... See more keywords