Bottom-Up Signal Boosting with Fractal Nanostructuring and Primer Exchange Reaction for Ultrasensitive Detection of Cancerous Exosomes.
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DOI: 10.1021/acssensors.2c02819
Abstract: Exosomes are emerging as promising biomarkers for cancer diagnosis, yet sensitive and accurate quantification of tumor-derived exosomes remains a challenge. Here, we report an ultrasensitive and specific exosome sensor (NPExo) that initially leverages hierarchical nanostructuring… read more here.
Keywords: cancerous exosomes; exchange reaction; bottom signal; signal boosting ... See more keywords