Improving Confidence in the Determination of Free Fraction for Highly Bound Drugs Using Bidirectional Equilibrium Dialysis.
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DOI: 10.1016/j.xphs.2018.10.011
Abstract: Equilibrium dialysis has been widely used for the measurement of the fraction of unbound drug (fu) in plasma, but it suffers from the accuracy and reliability for low fu values. To address this concern, an… read more here.
Keywords: bound drugs; highly bound; equilibrium dialysis; bidirectional equilibrium ... See more keywords