C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2102787118
Abstract: Significance Antibody-dependent complement activation plays a major role in various pathophysiological processes in our body, including infection, inflammation, autoimmunity, and transplant rejection. In order to activate complement, antibodies should bind to target cells and recruit… read more here.
Keywords: surface bound; bound igg; c1r2s2 proteases; igg ... See more keywords
P-323 Immunoglobulin G Selectively Identifies Pathosymbionts in Paediatric Inflammatory Bowel Diseases
Sign Up to like & getrecommendations! Published in 2017 at "Inflammatory Bowel Diseases"
DOI: 10.1097/01.mib.0000512864.34774.10
Abstract: Background: Inflammatory bowel diseases (IBD) are a group of complex and multifactorial disorders with unknown etiology. Both environmental and genetic factors contribute to disease pathogenesis. This complexity is further exacerbated with an uncontrolled immune response… read more here.
Keywords: igg; inflammatory bowel; bowel diseases; ibd ... See more keywords