Therapeutic activation of endothelial sphingosine‐1‐phosphate receptor 1 by chaperone‐bound S1P suppresses proliferative retinal neovascularization
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DOI: 10.15252/emmm.202216645
Abstract: Sphingosine‐1‐phosphate (S1P), the circulating HDL‐bound lipid mediator that acts via S1P receptors (S1PR), is required for normal vascular development. The role of this signaling axis in vascular retinopathies is unclear. Here, we show in a… read more here.
Keywords: activation endothelial; bound s1p; s1p; sphingosine phosphate ... See more keywords