Ribosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance
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DOI: 10.1261/rna.079416.122
Abstract: Upf1, Upf2, and Upf3, the central regulators of nonsense-mediated mRNA decay (NMD), appear to exercise their NMD functions while bound to elongating ribosomes, and evidence for this conclusion is particularly compelling for Upf1. Hence, we… read more here.
Keywords: mrna surveillance; ribosome bound; upf1 forms; ribosome ... See more keywords