Robust boundary formation in a morphogen gradient via cell-cell signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Physical review. E"
DOI: 10.1103/physreve.105.064405
Abstract: Establishing sharp and correctly positioned boundaries in spatial gene expression patterns is a central task in both developmental and synthetic biology. We consider situations where a global morphogen gradient provides positional information to cells but… read more here.
Keywords: morphogen gradient; cell; boundary formation;
Essential role of Cp190 in physical and regulatory boundary formation
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abl8834
Abstract: Boundaries in animal genomes delimit contact domains with enhanced internal contact frequencies and have debated functions in limiting regulatory cross-talk between domains and guiding enhancers to target promoters. Most mammalian boundaries form by stalling of… read more here.
Keywords: essential role; boundaries form; cp190; boundary formation ... See more keywords
Modeling and analysis of the Delta-Notch dependent boundary formation in the Drosophila large intestine
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DOI: 10.1186/s12918-017-0455-8
Abstract: BackgroundThe boundary formation in the Drosophila large intestine is widely studied as an important biological problem. It has been shown that the Delta-Notch signaling pathway plays an essential role in the formation of boundary cells.ResultsIn… read more here.
Keywords: formation; formation drosophila; delta notch; large intestine ... See more keywords
Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna
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DOI: 10.1371/journal.pgen.1006898
Abstract: Compartment boundary formation plays an important role in development by separating adjacent developmental fields. Drosophila imaginal discs have proven valuable for studying the mechanisms of boundary formation. We studied the boundary separating the proximal A1… read more here.
Keywords: developmental fields; epithelial fold; dll; formation ... See more keywords
Spt3 and Spt8 Are Involved in the Formation of a Silencing Boundary by Interacting with TATA-Binding Protein
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DOI: 10.3390/biom13040619
Abstract: In Saccharomyces cerevisiae, a heterochromatin-like chromatin structure called the silencing region is present at the telomere as a complex of Sir2, Sir3, and Sir4. Although spreading of the silencing region is blocked by histone acetylase-mediated… read more here.
Keywords: formation; spt3 spt8; tata binding; boundary formation ... See more keywords