Bovine single chain Fv antibody inhibits bovine herpesvirus-1 infectivity by targeting viral glycoprotein D
Sign Up to like & getrecommendations! Published in 2017 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-017-8566-0
Abstract: Glycoprotein D (gD) of bovine herpesvirus-1 (BoHV-1) is essential for attachment and penetration of cells during infection and is a major target for neutralizing antibodies during an adaptive immune response. Currently there are no recombinant… read more here.
Keywords: chain antibody; bovine; bovine herpesvirus; bohv ... See more keywords
Novel Polymerase Spiral Reaction (PSR) for rapid visual detection of Bovine Herpesvirus 1 genomic DNA from aborted bovine fetus and semen.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2017.11.004
Abstract: Bovine herpesvirus-1 (BHV-1) is a major viral pathogen affecting bovines leading to various clinical manifestations and causes significant economic impediment in modern livestock production system. Rapid, accurate and sensitive detection of BHV-1 infection at frozen… read more here.
Keywords: detection; dna; bovine herpesvirus; psr ... See more keywords
Prevention of abortion in cattle following vaccination against bovine herpesvirus 1: A meta-analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Preventive veterinary medicine"
DOI: 10.1016/j.prevetmed.2017.01.005
Abstract: Bovine herpesvirus 1 is ubiquitous in cattle populations and is the cause of several clinical syndromes including respiratory disease, genital disease, and late-term abortions. Control of the virus in many parts of the world is… read more here.
Keywords: vaccination; abortion; bovine herpesvirus; meta analysis ... See more keywords
Immune responses in bovines to recombinant glycoprotein D of bovine herpesvirus type 5 as vaccine antigen.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.10.080
Abstract: Bovine herpesvirus 5 (BoHV-5) is responsible for outbreaks of meningoencephalitis that cause important economic losses in young cattle. BoHV-5 glycoprotein D (gD5) is essential for attachment and penetration into permissive cells and targeting of host… read more here.
Keywords: bovine herpesvirus; group; bohv; vaccine ... See more keywords
β-cantenin is potentially involved in the regulation of c-Jun signaling following bovine herpesvirus 1 infection
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary Microbiology"
DOI: 10.1016/j.vetmic.2020.108804
Abstract: Abstract C-Jun, activated by various extracellular signals, is important for cell differentiation, proliferation, apoptosis, and inflammatory responses. We have previously reported that bovine herpesvirus 1 (BoHV-1) infection in MDBK cells stimulates the c-Jun NH2-terminal kinase… read more here.
Keywords: jun; bovine herpesvirus; infection; bohv infection ... See more keywords
Effects of the synthetic corticosteroid dexamethasone on bovine herpesvirus 1 productive infection.
Sign Up to like & getrecommendations! Published in 2017 at "Virology"
DOI: 10.1016/j.virol.2017.02.012
Abstract: Sensory neurons are a primary site for life-long latency of bovine herpesvirus 1 (BoHV-1). The synthetic corticosteroid dexamethasone induces reactivation from latency and productive infection, in part because the BoHV-1 genome contains more than 100… read more here.
Keywords: corticosteroid dexamethasone; bovine herpesvirus; synthetic corticosteroid; infection ... See more keywords
MG-132 reduces virus release in Bovine herpesvirus-1 infection
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DOI: 10.1038/s41598-017-13717-1
Abstract: Bovine herpesvirus 1 (BoHV-1) can provoke conjunctivitis, abortions and shipping fever. BoHV-1 infection can also cause immunosuppression and increased susceptibility to secondary bacterial infections, leading to pneumonia and occasionally to death. Herein, we investigated the… read more here.
Keywords: bovine herpesvirus; infection; virus release;
Induction of Both Local Immune Response in Mice and Protection in a Rabbit Model by Intranasal Immunization with Modified Vaccinia Ankara Virus Expressing a Secreted Form of Bovine Herpesvirus 1 Glycoprotein D.
Sign Up to like & getrecommendations! Published in 2017 at "Viral immunology"
DOI: 10.1089/vim.2016.0090
Abstract: In this study, we evaluated the immunogenicity and efficacy of mucosal delivery of a recombinant modified vaccinia Ankara virus (MVA) expressing the secreted version of bovine herpesvirus type 1 (BoHV-1) glycoprotein D (MVA-gDs) without addition… read more here.
Keywords: immune; ankara virus; modified vaccinia; vaccinia ankara ... See more keywords
An Improved DNA Vaccine Against Bovine Herpesvirus-1 Using CD40L and a Chemical Adjuvant Induces Specific Cytotoxicity in Mice.
Sign Up to like & getrecommendations! Published in 2020 at "Viral immunology"
DOI: 10.1089/vim.2020.0082
Abstract: Bovine herpesvirus-1 (BoHV-1) uses many mechanisms to elude the immune system; one of them is spreading intracellularly, even in the presence of specific antiviral antibodies. Cytotoxic T lymphocytes (CTLs) are necessary to eliminate the virus.… read more here.
Keywords: vaccine; bovine herpesvirus; dna vaccine; pcigd ... See more keywords
Bovine Herpesvirus 1 Invasion of Sensory Neurons by Retrograde Axonal Transport Is Dependent on the pUL37 Region 2 Effector
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01486-21
Abstract: A molecular and cellular understanding of the retrograde axonal transport process that underlies the neuroinvasive properties of the alphaherpesviruses is established from studies of herpes simplex virus and pseudorabies virus. The degree to which this… read more here.
Keywords: pul37 region; axonal transport; transport; retrograde axonal ... See more keywords
Bovine Herpesvirus 1 Productive Infection Led to Inactivation of Nrf2 Signaling through Diverse Approaches
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/4957878
Abstract: Bovine herpesvirus type 1 (BoHV-1) is a significant cofactor for bovine respiratory disease complex (BRDC), the most important inflammatory disease in cattle. BoHV-1 infection in cell cultures induces overproduction of pathogenic reactive oxygen species (ROS)… read more here.
Keywords: bovine herpesvirus; infection; nrf2 signaling; bohv infection ... See more keywords