Prevalence of mismatch repair deficiency and Lynch syndrome in a cohort of unselected small bowel adenocarcinomas
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2020-207040
Abstract: Aims Previous estimates of the prevalence of mismatch repair (MMR) deficiency and Lynch syndrome in small bowel cancer have varied widely. The aim of this study was to establish the prevalence of MMR deficiency and… read more here.
Keywords: small bowel; bowel; prevalence; bowel adenocarcinomas ... See more keywords
DNA sequencing of the small bowel adenocarcinomas to identify targetable ErbB2 mutations.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e15800
Abstract: e15800Background: Small bowel adenocarcinoma (SBA) is a rare malignancy of the digestive tract with limited knowledge about its genetic alterations. Methods: Eighteen tumor and normal matched samples were sequenced using the whole-exome-Illumina platform. Various agnostic… read more here.
Keywords: small bowel; dna sequencing; sequencing small; erbb2 mutations ... See more keywords
Incidence, treatment and survival outcomes of small bowel adenocarcinomas: A National Cancer Database (NCDB) analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e16262
Abstract: e16262Background: Small bowel adenocarcinomas (SBA) are rare tumors. Management of SBA is extrapolated from colorectal cancer treatments. Recent evidence suggests that the biology and molecular fea... read more here.
Keywords: small bowel; incidence treatment; bowel adenocarcinomas; cancer ... See more keywords
ASO Author Reflections: Prognostication in Early- and Advanced-Stage Small Bowel Adenocarcinomas
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DOI: 10.1245/s10434-020-08936-2
Abstract: Small bowel adenocarcinomas (SBAs) are rare and poorly investigated cancers. Therefore, for a long time, therapeutic approaches for these neoplasms have been mainly extrapolated from colorectal cancer studies. Compelling evidence that SBA is a distinct… read more here.
Keywords: bowel adenocarcinomas; small bowel; stage; aso author ... See more keywords