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Published in 2017 at "Results and problems in cell differentiation"
DOI: 10.1007/978-3-319-60855-6_6
Abstract: The DEAD-box helicase Vasa (Vas) has been most extensively studied in the fruit fly, Drosophila melanogaster, and numerous roles for it in germline development have been discovered. Here, we summarize the present state of knowledge…
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Keywords:
helicase vasa;
box helicase;
dead box;
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Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2019.12.021
Abstract: Embryonic stem cells (ESCs) exhibit high levels of ribosomal RNA (rRNA) transcription and ribosome biogenesis. Here, we reveal an unexpected role for an essential DEAD-box helicase, DDX18, in antagonizing the polycomb repressive complex 2 (PRC2)…
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Keywords:
box helicase;
ddx18;
counteracts prc2;
dead box ... See more keywords
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Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108903
Abstract: Across the animal kingdom, adult tissue homeostasis is regulated by adult stem cell activity, which is commonly dysregulated in human cancers. However, identifying key regulators of stem cells in the milieu of thousands of genes…
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Keywords:
ddx56;
box helicase;
dead box;
cancer ... See more keywords
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Published in 2022 at "Methods"
DOI: 10.1016/j.ymeth.2022.03.002
Abstract: DDX43 (DEAD-box helicase 43), also known as HAGE (helicase antigen gene), is a member of the DEAD-box protein family. It contains a K homology (KH) domain in its N terminus, a helicase core domain in…
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Keywords:
helicase;
ddx43;
domain;
dead box ... See more keywords
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Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00755
Abstract: In recent years, globalization, global warming, and population aging have contributed to the spread of emerging viruses, such as coronaviruses (COVs), West Nile (WNV), Dengue (DENV), and Zika (ZIKV). The number of reported infections is…
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Keywords:
box helicase;
dead box;
emerging viruses;
helicase ... See more keywords
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Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2068923
Abstract: ABSTRACT Cerebral ischemia-reperfusion damages local brain tissue and impairs brain function, but its specific pathogenesis is still uncertain. Recent studies have clarified circPUM1 is aberrantly elevated in cerebral ischemia-reperfusion injury; however, circPUM1ʹs function in cerebral…
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Keywords:
box helicase;
microrna 340;
cerebral ischemia;
dead box ... See more keywords
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Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2084235
Abstract: ABSTRACT DEAD-box helicase (DDX) family exerts a critical effect on cancer initiation and progression through alternative splicing, transcription and ribosome biogenesis. Increasing evidence has demonstrated that DEAD-box helicase 56 (DDX56) is over-expressed in several cancers,…
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Keywords:
cell;
box helicase;
ddx56;
dead box ... See more keywords
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Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1059159
Abstract: Objective To determine the genetic etiology of a family pedigree with two patients affected by differences of sex development (DSD). Methods Assess the clinical characteristics of the patients and achieve exome sequencing results and in…
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Keywords:
box helicase;
sex development;
differences sex;
sex ... See more keywords