Identification, expression analysis, and function evaluation of 42 tomato DEAD-box RNA helicase genes in growth development and stress response
Sign Up to like & getrecommendations! Published in 2018 at "Acta Physiologiae Plantarum"
DOI: 10.1007/s11738-018-2665-0
Abstract: DEAD-box RNA helicases play pivotal roles in almost all processes in RNA metabolisms, associated with various cellular functions including plant development and the response to abiotic stress. Previously, although DEAD-box genes were identified in tomato… read more here.
Keywords: dead box; stress; box; box rna ... See more keywords
Knockdown of DEAD-box RNA helicase DDX5 selectively attenuates serine 311 phosphorylation of NF-κB p65 subunit and expression level of anti-apoptotic factor Bcl-2.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2019.109428
Abstract: NF-κB plays a key role in the transcriptional regulation of genes involved in immunity, inflammation, cell proliferation, and oncogenesis. The NF-κB activation process includes nuclear translocation, followed by association with basal transcription machinery. These steps… read more here.
Keywords: expression level; rna helicase; dead box; phosphorylation p65 ... See more keywords
Evaluation of antileishmanial potential of computationally screened compounds targeting DEAD-box RNA helicase of Leishmania donovani.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.10.053
Abstract: Visceral leishmaniasis (VL) is one of the most devastating diseases of the tropical region caused by protozoan parasite Leishmania donovani. So far, there is no effective drug and vaccine available against this fatal disease. The… read more here.
Keywords: rna helicase; rna; dead box; donovani ... See more keywords
DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c8cc10091h
Abstract: We identified 29 G-quadruplex binding proteins by affinity purification and quantitative LC-MS/MS. We demonstrated that the DEAD-box RNA helicases Dbp2, Ded1 and Mss116 preferentially bind to G-quadruplex nucleic acids in vitro and destabilize RNA quadruplexes,… read more here.
Keywords: rna; dead box; helicases dbp2; rna helicases ... See more keywords
The DEAD-box RNA helicase RhlE2 is a global regulator of Pseudomonas aeruginosa lifestyle and pathogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab503
Abstract: Abstract RNA helicases perform essential housekeeping and regulatory functions in all domains of life by binding and unwinding RNA molecules. The bacterial RhlE-like DEAD-box RNA helicases are among the least well studied of these enzymes.… read more here.
Keywords: pseudomonas aeruginosa; rna; rhle2; dead box ... See more keywords
Association of the Cold Shock DEAD-Box RNA Helicase RhlE to the RNA Degradosome in Caulobacter crescentus
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bacteriology"
DOI: 10.1128/jb.00135-17
Abstract: ABSTRACT In diverse bacterial lineages, multienzyme assemblies have evolved that are central elements of RNA metabolism and RNA-mediated regulation. The aquatic Gram-negative bacterium Caulobacter crescentus, which has been a model system for studying the bacterial… read more here.
Keywords: temperature; rna degradosome; rna; dead box ... See more keywords
The Sole DEAD-Box RNA Helicase of the Gastric Pathogen Helicobacter pylori Is Essential for Colonization
Sign Up to like & getrecommendations! Published in 2018 at "mBio"
DOI: 10.1128/mbio.02071-17
Abstract: ABSTRACT Present in every kingdom of life, generally in multiple copies, DEAD-box RNA helicases are specialized enzymes that unwind RNA secondary structures. They play major roles in mRNA decay, ribosome biogenesis, and adaptation to cold… read more here.
Keywords: role; box rna; helicase; dead box ... See more keywords
The DEAD-Box RNA Helicase DDX3 Interacts with m6A RNA Demethylase ALKBH5
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells International"
DOI: 10.1155/2017/8596135
Abstract: DDX3 is a member of the family of DEAD-box RNA helicases. DDX3 is a multifaceted helicase and plays essential roles in key biological processes such as cell cycle, stress response, apoptosis, and RNA metabolism. In… read more here.
Keywords: alkbh5; ddx3; rna; dead box ... See more keywords
The DEAD-Box RNA Helicases of Bacillus subtilis as a Model to Evaluate Genetic Compensation Among Duplicate Genes
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.02261
Abstract: The presence of duplicated genes in organisms is well documented. There is increasing interest in understanding how these genes subfunctionalize and whether functional overlap can explain the fact that some of these genes are dispensable.… read more here.
Keywords: rna; dead box; rna helicases; bacillus subtilis ... See more keywords
High Levels of DEAH-Box Helicases Relate to Poor Prognosis and Reduction of DHX9 Improves Radiosensitivity of Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.900671
Abstract: Background Liver hepatocellular carcinoma (LIHC), one of the most common primary malignancies, exhibits high levels of molecular and clinical heterogeneity. Increasing evidence has confirmed the important roles of some RNA helicase families in tumor development,… read more here.
Keywords: box; deah box; box rna; dhx9 ... See more keywords
The In Silico Identification of Potential Members of the Ded1/DDX3 Subfamily of DEAD-Box RNA Helicases from the Protozoan Parasite Leishmania infantum and Their Analyses in Yeast
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.3390/genes12020212
Abstract: DEAD-box RNA helicases are ubiquitous proteins found in all kingdoms of life and that are associated with all processes involving RNA. Their central roles in biology make these proteins potential targets for therapeutic or prophylactic… read more here.
Keywords: ded1 ddx3; dead box; box; ddx3 subfamily ... See more keywords