Challenge Integrity: The Cell-Penetrating Peptide BP100 Interferes with the Auxin–Actin Oscillator
Sign Up to like & getrecommendations! Published in 2017 at "Plant and Cell Physiology"
DOI: 10.1093/pcp/pcw161
Abstract: Actin filaments are essential for the integrity of the cell membrane. In addition to this structural role, actin can modulate signaling by altering polar auxin flow. On the other hand, the organization of actin filaments… read more here.
Keywords: actin; integrity; auxin actin; bp100 ... See more keywords
RW-BP100-4D, a Promising Antimicrobial Candidate With Broad-Spectrum Bactericidal Activity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.815980
Abstract: With the rapid emergence and dissemination of antimicrobial resistance (AMR) genes in bacteria from animal, animal-derived food and human clinic, it is of great significance to develop new approaches to combat the multidrug-resistant bacteria. This… read more here.
Keywords: promising antimicrobial; antimicrobial candidate; activity; bp100 ... See more keywords
Naphthalimide-Containing BP100 Leads to Higher Model Membranes Interactions and Antimicrobial Activity
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11040542
Abstract: In a large variety of organisms, antimicrobial peptides (AMPs) are primary defenses against pathogens. BP100 (KKLFKKILKYL-NH2), a short, synthetic, cationic AMP, is active against bacteria and displays low toxicity towards eukaryotic cells. BP100 acquires a… read more here.
Keywords: dna; naphthalimide containing; containing bp100; bp100 ... See more keywords
The Unusual Aggregation and Fusion Activity of the Antimicrobial Peptide W-BP100 in Anionic Vesicles
Sign Up to like & getrecommendations! Published in 2023 at "Membranes"
DOI: 10.3390/membranes13020138
Abstract: Cationic antimicrobial peptides (CAMPs) offer a promising strategy to counteract bacterial resistance, mostly due to their membrane-targeting activity. W-BP100 is a potent broad-spectrum cecropin-melittin CAMP bearing a single N-terminal Trp, which was previously found to… read more here.
Keywords: aggregation; anionic vesicles; aggregation fusion; activity ... See more keywords