Pentadecapeptide BPC 157 counteracts L-NAME-induced catalepsy. BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat acute and chronic models resembling ‘positive-like’ symptoms of schizophrenia
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DOI: 10.1016/j.bbr.2020.112919
Abstract: In the suited rat-models, we focused on the stable pentadecapeptide BPC 157, L-NAME, NOS-inhibitor, and L-arginine, NOS-substrate, relation, the effect on schizophrenia-like symptoms. Medication (mg/kg intraperitoneally) was L-NAME (5), L-arginine (100), BPC 157 (0.01), given… read more here.
Keywords: induced catalepsy; bpc 157; name arginine; name ... See more keywords
BPC157 rescued NSAID-cytotoxicity via stabilizing intestinal permeability and enhancing cytoprotection.
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DOI: 10.2174/1381612826666200523180301
Abstract: The stable gastric pentadecapeptideBPC 157 protects stomach cells, maintains gastric integrity against various noxious agents such as alcohol, nonsteroidal anti-inflammatory drugs (NSAIDs), and exerts cytoprotection/adaptive cytoprotection/organoprotection in other epithelia, that is, skin, liver, pancreas, heart,… read more here.
Keywords: cytoprotection; rescued nsaid; permeability; bpc 157 ... See more keywords
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
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DOI: 10.3389/fphar.2021.627533
Abstract: Significance: The antiulcer peptide, stable gastric pentadecapeptide BPC 157 (previously employed in ulcerative colitis and multiple sclerosis trials, no reported toxicity (LD1 not achieved)), is reviewed, focusing on the particular skin wound therapy, incisional/excisional wound,… read more here.
Keywords: wound healing; stable gastric; wound; bpc 157 ... See more keywords
BPC 157 Therapy and the Permanent Occlusion of the Superior Sagittal Sinus in Rat: Vascular Recruitment
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DOI: 10.3390/biomedicines9070744
Abstract: We show the complex syndrome of the occluded superior sagittal sinus, brain swelling and lesions and multiple peripheral organs lesions in rat. Recovery goes centrally and peripherally, with the stable gastric pentadecapeptide BPC 157, which… read more here.
Keywords: sagittal sinus; bpc 157; 157 therapy; superior sagittal ... See more keywords
Stable Gastric Pentadecapeptide BPC 157 May Recover Brain–Gut Axis and Gut–Brain Axis Function
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DOI: 10.3390/ph16050676
Abstract: Conceptually, a wide beneficial effect, both peripherally and centrally, might have been essential for the harmony of brain–gut and gut–brain axes’ function. Seen from the original viewpoint of the gut peptides’ significance and brain relation,… read more here.
Keywords: function; gut; brain gut; brain ... See more keywords
Innate Vascular Failure by Application of Neuroleptics, Amphetamine, and Domperidone Rapidly Induced Severe Occlusion/Occlusion-like Syndromes in Rats and Stable Gastric Pentadecapeptide BPC 157 as Therapy
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DOI: 10.3390/ph16060788
Abstract: Even before behavioral disturbances, neuroleptics, amphetamine, and domperidone application rapidly emerged severe occlusion/occlusion-like syndrome, shared innate vascular and multiorgan failure in rats, comparable to occlusion/occlusion-like syndrome described with vessel(s) occlusion or similar noxious procedures application.… read more here.
Keywords: occlusion; 157 therapy; neuroleptics amphetamine; domperidone ... See more keywords