Finafloxacin overcomes Burkholderia pseudomallei efflux-mediated fluoroquinolone resistance
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw529
Abstract: Sir, Burkholderia pseudomallei is a biothreat agent and causes melioidosis, a globally emerging infectious disease with high case fatality rates, and B. pseudomallei infections are difficult to treat. Although curiously rare in B. pseudomallei, drug… read more here.
Keywords: finafloxacin; bpeef oprc; resistance; pseudomallei ... See more keywords
Molecular determinants of Burkholderia pseudomallei BpeEF-OprC efflux pump expression.
Sign Up to like & getrecommendations! Published in 2018 at "Microbiology"
DOI: 10.1099/mic.0.000691
Abstract: Burkholderia pseudomallei, the cause of melioidosis, is intrinsically resistant to many antibiotics. Acquired multidrug resistance, including resistance to doxycycline and co-trimoxazole used for melioidosis eradication phase therapy, is mainly attributed to constitutive expression of the… read more here.
Keywords: bpee bpef; bpet; bpeef oprc; oprc ... See more keywords