Articles with "bpifb4" as a keyword



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Longevity-Associated Variant of BPIFB4 Confers Neuroprotection in the STHdh Cell Model of Huntington Disease

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232315313

Abstract: Huntington’s disease (HD) is caused by the production of mutant Huntingtin (mHTT), characterized by long polyglutamine repeats with toxic effects. There are currently no clinically validated therapeutic agents that slow or halt HD progression, resulting… read more here.

Keywords: bpifb4; sthdh cell; huntington disease; associated variant ... See more keywords