Tau-PET in early cortical Alzheimer brain regions in relation to mild behavioral impairment in older adults with either normal cognition or mild cognitive impairment
Sign Up to like & getrecommendations! Published in 2024 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2024.02.006
Abstract: Mild Behavioral Impairment (MBI) leverages later-life emergent and persistent neuropsychiatric symptoms (NPS) to identify a high-risk group for incident dementia. Phosphorylated tau (p-tau) is a hallmark biological manifestation of Alzheimer disease (AD). We investigated associations… read more here.
Keywords: mild behavioral; behavioral impairment; braak; tau ... See more keywords
White Matter Degeneration Pathways Associated With Tau Deposition in Alzheimer Disease
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000207250
Abstract: Background and Objectives The dynamics of white matter (WM) changes are understudied in Alzheimer disease (AD). Our goal was to study the association between flortaucipir PET and WM health using neurite orientation dispersion and density… read more here.
Keywords: braak; degeneration; white matter; disease ... See more keywords
Multicenter 18F-PI-2620 PET for In Vivo Braak Staging of Tau Pathology in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12030458
Abstract: Tau aggregates accumulate in the Alzheimer’s disease (AD) brain according to the established Braak staging scheme and spread from transentorhinal over limbic regions to the neocortex. To impact the management of AD patients, an in… read more here.
Keywords: braak; tau; pet; 18f 2620 ... See more keywords