Blockade of Bradykinin receptors worsens the dystrophic phenotype of mdx mice: differential effects for B1 and B2 receptors
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DOI: 10.1007/s12079-017-0439-x
Abstract: The Kallikrein Kinin System (KKS) is a vasoactive peptide system with known functions in the maintenance of tissue homeostasis, renal function and blood pressure. The main effector peptide of KKS is Bradykinin (BK). This ligand… read more here.
Keywords: receptors worsens; worsens dystrophic; mdx mice; mdx ... See more keywords
Bradykinin in asthma: Modulation of airway inflammation and remodelling
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.03.017
Abstract: Abstract Bradykinin, a pro‐inflammatory molecule, and its related peptides have been studied for their effects on acute reactions in upper and lower airways, where they can be synthesised and metabolized after exposure to different stimuli… read more here.
Keywords: asthma modulation; inflammation; bradykinin asthma; bradykinin ... See more keywords
The expression of bradykinin and its receptors in spinal cord ischemia‐reperfusion injury rat model
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DOI: 10.1016/j.lfs.2018.12.034
Abstract: Objective: To investigate the expression and time‐dependent manner of bradykinin (BK) as well as its receptors (Bradykinin receptors 1 and 2, B1R and B2R) in spinal cord ischemia‐reperfusion injury (SCII) in rat model. Methods: Sprague‐Dawley… read more here.
Keywords: rat model; bradykinin receptors; expression; injury ... See more keywords
Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Activation of Bradykinin Receptors
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2019.00075
Abstract: Background: Plasmodium falciparum, the etiologic agent of malaria, is a major cause of infant death in Africa. Although research on the contact system has been revitalized by recent discoveries in the field of thrombosis, limited… read more here.
Keywords: erythrocytic stages; adhesion; plasmodium falciparum; bradykinin ... See more keywords
The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency
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DOI: 10.3390/ijms231810332
Abstract: Background: Hereditary angioedema (HAE) is a rare, genetic disease caused by the decreased level or function of the C1 inhibitor. The primary mediator of symptoms in HAE is bradykinin acting through its two receptors, namely… read more here.
Keywords: role bradykinin; hereditary angioedema; role; inhibitor ... See more keywords
A Systematic Review of Molecular Imaging Agents Targeting Bradykinin B1 and B2 Receptors
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DOI: 10.3390/ph13080199
Abstract: Kinins, bradykinin and kallidin are vasoactive peptides that signal through the bradykinin B1 and B2 receptors (B1R and B2R). B2R is constitutively expressed in healthy tissues and mediates responses such as vasodilation, fluid balance and… read more here.
Keywords: systematic review; imaging agents; agents targeting; bradykinin ... See more keywords