Unclassified sclerosing malignant melanomas with AKAP9-BRAF gene fusion: a report of two cases and review of BRAF fusions in melanocytic tumors
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2290-0
Abstract: The current classification of melanocytic tumors includes clinical, pathological, and molecular data. A subset of lesions remains difficult to classify according to these complex multilayer schemes. We report two cases of deeply infiltrating melanomas with… read more here.
Keywords: report two; akap9 braf; braf; melanocytic tumors ... See more keywords
Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Dermatology"
DOI: 10.1111/bjd.15436
Abstract: BRAF gene mutations can be found in approximately 50% of melanomas, but the most common BRAF mutation leads to substitution at residue 600 of the protein, from valine to glutamic acid. BRAFV600E occurs in up… read more here.
Keywords: gene mutations; braf; clinical implications; biology ... See more keywords
Prevalence of BRAF gene mutation in samples of primary and metastatic colorectal cancer: A meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of cancer care"
DOI: 10.1111/ecc.13160
Abstract: INTRODUCTION Understanding the prevalence and biology of BRAF gene can improve the treatment methods of cancerous patients. This study aims to estimate the prevalence of BRAF gene mutation in samples of primary and metastatic colorectal… read more here.
Keywords: prevalence; gene mutation; gene; braf gene ... See more keywords
The Prognostic Significance of BRAF Gene Analysis in Children and Adolescents with Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis
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DOI: 10.3390/diagnostics13061187
Abstract: Thyroid cancer represents the prominent endocrine cancer in children. Papillary thyroid cancer (PTC) constitutes its most frequent (>90%) pediatric histological type. Mutations energizing the mitogen-activated-protein kinase (MAPK) pathway are definitely related to PTC. Its most… read more here.
Keywords: meta; analysis; braf gene; children adolescents ... See more keywords