Abstract LB-A35: Discovery of a new kinase inhibitor targeting BRAF monomers and dimers
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DOI: 10.1158/1535-7163.targ-17-lb-a35
Abstract: Increased activation of the RAS/RAF/MEK/ERK signaling pathway, through mutations in upstream activators or in components of the pathway, can lead to uncontrolled cellular growth and proliferation leading to tumor development. BRAF mutations are present in… read more here.
Keywords: braf monomers; kinase; braf; kinase inhibitor ... See more keywords