Analysis of the BRAFV600E mutation in 19 cases of Langerhans cell histiocytosis in Japan
Sign Up to like & getrecommendations! Published in 2017 at "Hematological Oncology"
DOI: 10.1002/hon.2293
Abstract: Langerhans cell histiocytosis (LCH) is a rare disease characterized by clonal proliferation of CD1a‐ and CD207 (langerin)‐positive dendritic cells. Mutated BRAF (p.V600E) is observed in histiocyte‐related diseases and dendritic cell‐related diseases, including LCH. BRAFV600E is… read more here.
Keywords: langerhans cell; analysis; brafv600e mutation; cell histiocytosis ... See more keywords
Abdominal involvement in Erdheim-Chester disease (ECD): MRI and CT imaging findings and their association with BRAFV600E mutation
Sign Up to like & getrecommendations! Published in 2018 at "European Radiology"
DOI: 10.1007/s00330-018-5326-1
Abstract: ObjectivesTo use magnetic resonance imaging (MRI) and computed tomography (CT) to define abdominal involvement in Erdheim–Chester disease (ECD), and to investigate the association between these findings and the BRAFV600E mutation.MethodsThis prospective study was performed on… read more here.
Keywords: erdheim chester; infiltration; brafv600e mutation; association ... See more keywords
Clinical significance of the BRAFV600E mutation in Asian patients with colorectal cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-018-3095-6
Abstract: BackgroundTo investigate the clinicopathological features and prognostic significance of the BRAFV600E mutation in Asian patients with colorectal cancer.MethodsWe retrospectively reviewed the medical records of 1969 patients with colorectal cancer admitted to Taipei Veterans General Hospital… read more here.
Keywords: patients colorectal; brafv600e mutation; colorectal cancer; brafv600e ... See more keywords
Association Between BRAFV600E Mutation and the American College of Radiology Thyroid Imaging, Reporting and Data System in Solitary Papillary Thyroid Carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Academic radiology"
DOI: 10.1016/j.acra.2018.05.010
Abstract: RATIONALE AND OBJECTIVES The purpose of this study was to evaluate the associations between BRAFV600E mutation, the American College of Radiology (ACR) thyroid imaging, reporting and data system (TI-RADS) on ultrasound and clinicopathological characteristics in… read more here.
Keywords: radiology; papillary thyroid; brafv600e mutation; mutation ... See more keywords
High-accuracy Detection of Preoperative Thyroid Nodules Using Combination of BRAFV600E Mutation and TMPRSS4 mRNA Level.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2018.11.003
Abstract: BACKGROUND Papillary thyroid cancer (PTC) is the most common epithelial thyroid tumor, accounting for more than 80% of all thyroid cancers. Though the fine needle aspiration biopsy (FNAB) represents as the golden standard for the… read more here.
Keywords: thyroid nodules; brafv600e mutation; accuracy; mrna level ... See more keywords
Role of ultrasonographic features and quantified BRAFV600E mutation in lymph node metastasis in Chinese patients with papillary thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-018-36171-z
Abstract: The association between cervical lymph node metastasis (LNM) and ultrasonographic features as well as BRAFV600E mutations in patients with papillary thyroid carcinoma (PTC) remained controversial. This study investigated the association between LNM and ultrasonographic features… read more here.
Keywords: lymph node; brafv600e mutation; ultrasonographic features; node metastasis ... See more keywords
Detection of BRAFV600E Mutation in Melanoma Patients by Digital PCR of Circulating DNA.
Sign Up to like & getrecommendations! Published in 2019 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2018.0193
Abstract: AIMS About 50% of melanomas have the BRAFV600E mutation. This mutation is an attractive therapeutic target. The aims of our study were to detect BRAFV600E mutations within circulating cell-free DNA in plasma ("liquid biopsy") by… read more here.
Keywords: melanoma; detection brafv600e; brafv600e mutation; digital pcr ... See more keywords
Optic tract edema in craniopharyngioma as a predictor of BRAFV600E mutation presence.
Sign Up to like & getrecommendations! Published in 2023 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyad003
Abstract: OBJECTIVE the advent of BRAF inhibitors for preoperative treatment of craniopharyngioma has necessitated the identification of BRAFV600E status. Hence, we investigated predictors of BRAFV600E mutation in craniopharyngiomas. METHODS this retrospective study utilized data from 30… read more here.
Keywords: optic tract; mutation; tract edema; brafv600e mutation ... See more keywords
PRKCA D463H Mutation in Chordoid Glioma of the Third Ventricle: A Cohort of 16 Cases, Including Two Cases Harboring BRAFV600E Mutation.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlaa107
Abstract: Chordoid gliomas (CG) of the third ventricle are characterized by chordoid and glial features, but the extent of histological variations across CG is not fully understood. Herein, we report 16 consecutive cases of CG. All… read more here.
Keywords: brafv600e mutation; third ventricle; two cases; cases including ... See more keywords
Delayed diagnosis of pituitary LCH with BRAFV600E mutation: A case report and literature review
Sign Up to like & getrecommendations! Published in 2025 at "Medicine"
DOI: 10.1097/md.0000000000045274
Abstract: Rationale: This case report highlights the diagnostic challenges and clinical complexities of adult-onset pituitary Langerhans Cell Histiocytosis (LCH), a rare entity with a prolonged and indolent progression. This underscores the critical need for heightened clinical… read more here.
Keywords: lch; brafv600e mutation; case report;
Can mutation abundance assess the biological behavior of BRAFV600E-positive papillary thyroid carcinoma?
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-025-06493-4
Abstract: BRAFV600E mutation is the most common genetic change in papillary thyroid carcinoma (PTC). Nevertheless, the association between BRAFV600E mutation status and abundance and the biological behavior of PTC is unclear. Thus, this study investigated whether… read more here.
Keywords: abundance; mutation abundance; brafv600e mutation; model ... See more keywords