Technical Note: Quality assurance of proton central axis pencil-beam spread-out Bragg peak using large-diameter multilayer ionization chambers.
Sign Up to like & getrecommendations! Published in 2019 at "Medical physics"
DOI: 10.1002/mp.13732
Abstract: PURPOSE The aim of this work is to describe a method of machine quality assurance (QA) by measuring proton spread-out Bragg peak constructed by the integrated depth dose via a large-diameter (12-cm) multilayer ionization chamber… read more here.
Keywords: large diameter; energy; spread bragg; bragg peak ... See more keywords
First application of a high resolution silicon detector for proton beam Bragg peak detection in a 0.95 T magnetic field.
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DOI: 10.1002/mp.13871
Abstract: PURPOSE To report on experimental results of a high spatial resolution silicon based detector exposed to therapeutic quality proton beams in a 0.95 T transverse magnetic field. These experimental results are important for the development… read more here.
Keywords: resolution; proton; detector; bragg peak ... See more keywords
Dose and Dose Rate objectives in Bragg peak and shoot-through beam orientation optimization for FLASH proton therapy.
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DOI: 10.1002/mp.16009
Abstract: PURPOSE The combined use of Bragg peak and shoot-through beams has previously been shown to increase the normal tissue volume receiving FLASH dose rates while maintaining dose conformality compared to conventional IMPT methods. However, the… read more here.
Keywords: beam orientation; dose rate; rate; bragg peak ... See more keywords
Implementation of a novel pencil beam scanning Bragg peak FLASH technique to a commercial treatment planning system
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DOI: 10.1002/mp.17876
Abstract: Ultra‐high dose rate, or FLASH, radiotherapy has shown promise in preclinical experiments of sparing healthy tissue without compromising tumor control. This “FLASH effect” can compound with dosimetric sparing of the proton Bragg peak (BP) using… read more here.
Keywords: flash; implementation novel; novel pencil; treatment planning ... See more keywords
An MCNPX2.7.0 study of Bragg peak degradation owing to density heterogeneity patterns for a CGMH therapeutic proton beam
Sign Up to like & getrecommendations! Published in 2017 at "Radiation Physics and Chemistry"
DOI: 10.1016/j.radphyschem.2016.01.014
Abstract: Abstract The purpose of this study was to investigate the density heterogeneity pattern as a factor affecting Bragg peak degradation, including shifts in Bragg peak depth (ZBP), distal range (R80 and R20), and distal fall-off… read more here.
Keywords: density heterogeneity; heterogeneity; density; bragg peak ... See more keywords
Monoenergetic 290 MeV/n carbon-ion beam biological lethal dose distribution surrounding the Bragg peak
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DOI: 10.1038/s41598-019-42600-4
Abstract: The sharp high dose Bragg peak of a carbon-ion beam helps it to deliver the highest dosage to the malignant cells while leaving the normal cells relatively unharmed. However, the precise range in which it… read more here.
Keywords: bragg peak; carbon ion; carbon;
Physiopathological effects of entrance versus distal spread-out Bragg peak on mouse spinal cord neurons
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DOI: 10.1038/s41598-024-84902-2
Abstract: Recent investigations into radiation-induced side effects have focused on understanding the physiopathological consequences of irradiation on late-responding tissues like the spinal cord, which can lead to chronic progressive myelopathy. Proton therapy, an advanced radiation treatment,… read more here.
Keywords: spinal cord; spread bragg; bragg peak;
DNA damage in blood leukocytes from mice irradiated with accelerated carbon ions with an energy of 450 MeV/nucleon
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2020.1807640
Abstract: Abstract Purpose The objective of the study was to estimate the DNA damage in blood leukocytes at long terms after irradiation of mice with carbon ions (450 MeV/nucleon) both before and in the Bragg peak. Materials… read more here.
Keywords: dna damage; carbon ions; bragg peak; blood ... See more keywords
A radiobiological study of carbon ions of different linear energy transfer in resistant human malignant cell lines
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DOI: 10.1080/09553002.2020.1820609
Abstract: Abstract Purpose Analysis of elimination of four human radioresistant malignant cell lines to mono-energetic and non mono-energetic incoming carbon ion beams, characterized by different linear energy transfer (LET) qualities is performed. Comparisons with protons from… read more here.
Keywords: carbon ions; carbon; cell lines; bragg peak ... See more keywords
Direct observation of electron density reconstruction at the metal-insulator transition in NaOs O 3
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DOI: 10.1103/physrevb.98.115116
Abstract: 5d transition metal oxides offer new opportunities to test our understanding of the interplay of correlation effects and spin-orbit interactions in materials in the absence of a single dominant interaction. The subtle balance between solid-state… read more here.
Keywords: insulator transition; transition; metal; bragg peak ... See more keywords
Proton range monitoring using 13N peak for proton therapy applications
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DOI: 10.1371/journal.pone.0263521
Abstract: The Monte Carlo method is employed in this study to simulate the proton irradiation of a water-gel phantom. Positron-emitting radionuclides such as 11C, 15O, and 13N are scored using the Particle and Heavy Ion Transport… read more here.
Keywords: incident proton; 13n peak; energy; bragg peak ... See more keywords