Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2022.4974
Abstract: Key Points Question To what extent are shared genetic determinants in the comorbidities and associations between gastrointestinal tract diseases and psychiatry disorders involved in the gut-brain axis? Findings In this genome-wide pleiotropic association study using… read more here.
Keywords: brain axis; shared genetic; etiology; gut brain ... See more keywords
Inflammation, Lifestyle Factors, and the Microbiome-Gut-Brain Axis: Relevance to Depression and Antidepressant Action.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2581
Abstract: Depression is considered a major public health concern, where existing pharmacological treatments are not equally effective across all patients. The pathogenesis of depression involves the interaction of complex biological components such as the immune system… read more here.
Keywords: gut brain; action; brain axis; depression ... See more keywords
Obesity and gut–microbiota–brain axis: A narrative review
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24420
Abstract: Obesity is a major health problem that is associated with many physiological and mental disorders, such as diabetes, stroke, and depression. Gut microbiota has been affirmed to interact with various organs, including the brain. Intestinal… read more here.
Keywords: brain axis; gut microbiota; brain; obesity ... See more keywords
The placenta‐brain‐axis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24603
Abstract: All mammalian species depend on the placenta, a transient organ, for exchange of gases, nutrients, and waste between the mother and conceptus. Besides serving as a conduit for such exchanges, the placenta produces hormones and… read more here.
Keywords: placenta; brain axis; physiology; placenta brain ... See more keywords
[From gut feeling to visceral pain : Effects of negative expectations in the context of the gut-brain axis].
Sign Up to like & getrecommendations! Published in 2021 at "Schmerz"
DOI: 10.1007/s00482-021-00614-w
Abstract: Disturbances of the gut-brain axis are characterized by complex dysfunctions on peripheral and central nervous system levels, which can contribute to visceral hypervigilance and hyperalgesia and imprint visceral pain. Numerous cognitive, emotional and psychoneurobiological factors… read more here.
Keywords: gut brain; visceral pain; brain axis; pain ... See more keywords
The Role of Epigenomic Regulatory Pathways in the Gut-Brain Axis and Visceral Hyperalgesia.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-021-01108-0
Abstract: The gut-brain axis (GBA) is broadly accepted to describe the bidirectional circuit that links the gastrointestinal tract with the central nervous system (CNS). Interest in the GBA has grown dramatically over past two decades along… read more here.
Keywords: visceral hyperalgesia; hyperalgesia; brain axis; epigenomic regulatory ... See more keywords
Sex Differences in the Gut-Brain Axis: Implications for Mental Health
Sign Up to like & getrecommendations! Published in 2020 at "Current Psychiatry Reports"
DOI: 10.1007/s11920-020-01202-y
Abstract: Purpose of Review The purpose of this article is to highlight how sex differences in the gut-brain axis may contribute to the discrepancies in incidence of neurodevelopmental, psychiatric, and neurodegenerative disorders between females and males.… read more here.
Keywords: differences gut; sex differences; brain axis; sex ... See more keywords
Inflammasome-Regulated Pyroptotic Cell Death in Disruption of the Gut-Brain Axis After Stroke.
Sign Up to like & getrecommendations! Published in 2022 at "Translational stroke research"
DOI: 10.1007/s12975-022-01005-8
Abstract: Approximately 50% of stroke survivors experience gastrointestinal complications. The innate immune response plays a role in changes to the gut-brain axis after stroke. The purpose of this study is to examine the importance of inflammasome-mediated… read more here.
Keywords: gut brain; disruption gut; brain axis; stroke ... See more keywords
The microbiota-gut-brain axis: Focus on the fundamental communication pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2020.08.012
Abstract: Abstract The existence of a bidirectional communication system termed the “gut-brain axis” linking the gastrointestinal tract with the brain has been recognized since the nineteenth century. In the last decades, however, it has become evident… read more here.
Keywords: microbiota gut; communication; brain axis; brain ... See more keywords
Neuropeptides in gut-brain axis and their influence on host immunity and stress
Sign Up to like & getrecommendations! Published in 2020 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2020.02.018
Abstract: In recent decades, neuropeptides have been found to play a major role in communication along the gut-brain axis. Various neuropeptides are expressed in the central and peripheral nervous systems, where they facilitate the crosstalk between… read more here.
Keywords: immunity stress; brain axis; nervous systems; brain ... See more keywords
Chronic periodontitis induces microbiota-gut-brain axis disorders and cognitive impairment in mice
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2020.113176
Abstract: Epidemiological studies suggest that chronic periodontitis (CP) is closely associated with the incidence and progression of cognitive impairment. The present study investigated the causal relationship between CP and cognitive decline and the underlying mechanism in… read more here.
Keywords: microbiota gut; gut; brain axis; cognitive impairment ... See more keywords