Traumatic Brain Injury and Subsequent Risk of Brain Cancer in US Veterans of the Iraq and Afghanistan Wars
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.54588
Abstract: Key Points Question Is traumatic brain injury (TBI) associated with the subsequent risk of brain cancer in Iraq and Afghanistan veterans? Findings In this cohort study of more than 1.9 million veterans, moderate or severe… read more here.
Keywords: traumatic brain; brain; brain injury; risk ... See more keywords
Understanding brain cancer and exploiting its vulnerabilities
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13769
Abstract: Brain cancer is one of the most devastating neoplasms affecting both children and adults. Its dismal prognosis has for long‐time discouraged research in this area. However, in the last 10–15 years remarkable progress has been made… read more here.
Keywords: cancer; understanding brain; brain; cancer exploiting ... See more keywords
Lipid Nanoparticles: Versatile Drug Delivery Vehicles for Traversing the Blood Brain Barrier to Treat Brain Cancer
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202404234
Abstract: The blood‐brain barrier (BBB) poses a significant challenge in delivering therapeutic agents for brain diseases due to its high selectivity against foreign substances. This limitation greatly hampers the effectiveness of conventional chemotherapeutic drugs in treating… read more here.
Keywords: cancer; brain; barrier; brain cancer ... See more keywords
Molecular mechanism(s) of regulations of cancer stem cell in brain cancer propagation
Sign Up to like & getrecommendations! Published in 2022 at "Medicinal Research Reviews"
DOI: 10.1002/med.21930
Abstract: Brain tumors are most often diagnosed with solid neoplasms and are the primary reason for cancer‐related deaths in both children and adults worldwide. With recent developments in the progression of novel targeted chemotherapies, the prognosis… read more here.
Keywords: brain cancer; cancer; cancer stem; brain ... See more keywords
Anti-miRNA- 155 - 5p enhances the cytotoxic efficacy of temozolomide in brain cancer stem cells
Sign Up to like & getrecommendations! Published in 2025 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-025-04135-6
Abstract: This study aimed to assess the molecular effects of the miR- 155 - 5p in modulating Temozolomide chemosensitivity, which was examined utilizing in silico and in vitro methods on brain cancer stem cells (BCSCs) that exhibit… read more here.
Keywords: mir 155; brain cancer; stem cells; cancer stem ... See more keywords
Role of key genetic mutations on increasing migration of brain cancer cells through confinement
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical Microdevices"
DOI: 10.1007/s10544-017-0197-9
Abstract: Uncontrolled invasive cancer cell migration is among the major challenges for the treatment and management of brain cancer. Although the genetic profiles of brain cancer cells have been well characterized, the relationship between the genetic… read more here.
Keywords: brain cancer; confinement; migration; genetic mutations ... See more keywords
CT scans in childhood predict subsequent brain cancer: Finite mixture modelling can help separate reverse causation scans from those that may be causal.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer epidemiology"
DOI: 10.1016/j.canep.2020.101732
Abstract: BACKGROUND Excess brain cancers observed after computed tomography (CT) scans could be caused by ionizing radiation. However, as scans are often used to investigate symptoms of brain cancer, excess cancers could also be due to… read more here.
Keywords: brain cancer; reverse causation; cancer; mixture ... See more keywords
Vessel-Targeting Nanoclovers Enable Noninvasive Delivery of Magnetic Hyperthermia-Chemotherapy Combination for Brain Cancer Treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Nano letters"
DOI: 10.1021/acs.nanolett.1c02459
Abstract: Despite being promising, the clinical application of magnetic hyperthermia for brain cancer treatment is limited by the requirement of highly invasive intracranial injections. To overcome this limitation, here we report the development of gallic acid-coated… read more here.
Keywords: brain cancer; delivery; brain; magnetic hyperthermia ... See more keywords
Hydroxyapatite as a Vehicle for the Selective Effect of Superparamagnetic Iron Oxide Nanoparticles against Human Glioblastoma Cells.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b15116
Abstract: Despite the early promises of magnetic hyperthermia (MH) as a method for treating cancer, it has been stagnating in the past decade. Some of the reasons for the low effectiveness of superparamagnetic nanoparticles (SPIONs) in… read more here.
Keywords: brain cancer; healthy cells; cancer cells; cancer ... See more keywords
DEEP Surveillance of Brain Cancer Using Self-Functionalized 3D Nanoprobes for Noninvasive Liquid Biopsy.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c04187
Abstract: Brain cancers, one of the most fatal malignancies, require accurate diagnosis for guided therapeutic intervention. However, conventional methods for brain cancer prognosis (imaging and tissue biopsy) face challenges due to the complex nature and inaccessible… read more here.
Keywords: brain cancer; liquid biopsy; brain; surveillance ... See more keywords
T cells engineered to home in on brain cancer
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-05883-7
Abstract: Immunotherapies activate T cells to destroy tumours, but the approach has failed in some brain cancers. A strategy to improve migration of T cells across the blood–brain barrier could overcome this limitation.A synthetic ligand enhances… read more here.
Keywords: brain cancer; cells engineered; engineered home; home brain ... See more keywords