Unveiling the Human Brain on a Chip: An Odyssey to Reconstitute Neuronal Ensembles and Explore Plausible Applications in Neuroscience.
Sign Up to like & getrecommendations! Published in 2024 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.4c00388
Abstract: The brain is an incredibly complex structure that consists of millions of neural networks. In developmental and cellular neuroscience, probing the highly complex dynamics of the brain remains a challenge. Furthermore, deciphering how several cues… read more here.
Keywords: brain; culture; cell; brain chip ... See more keywords
Microfluidic 'brain-on chip' systems to supplement neurological practice: development, applications and considerations.
Sign Up to like & getrecommendations! Published in 2023 at "Regenerative medicine"
DOI: 10.2217/rme-2022-0212
Abstract: Among the greatest general challenges in bioengineering is to mimic human physiology. Advanced efforts in tissue engineering have led to sophisticated 'brain-on-chip' (BoC) microfluidic devices that can mimic structural and functional aspects of brain tissue. BoC… read more here.
Keywords: practice; microfluidic brain; brain; brain chip ... See more keywords
Brain-on-a-Chip: A Human 3D Model for Clinical Application
Sign Up to like & getrecommendations! Published in 2019 at "Studies in health technology and informatics"
DOI: 10.3233/978-1-61499-975-1-274
Abstract: The main goal of this research is to design, develop and implement an efficient protocol to generate 3D neural cultures derived from human induced Pluripotent Stem Cells (hiPSCs) coupled to Micro Electrode Arrays (MEA) in… read more here.
Keywords: chip human; human model; brain; brain chip ... See more keywords
Brain-on-a-Chip: Dream or Reality?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.837623
Abstract: One of the dreams of neuroengineers is building a human brain. More realistically, building an accurate model of the brain with thousands of neurons synaptically connected to be used for a large variety of experiments… read more here.
Keywords: reality; human brain; brain chip; dream ... See more keywords
Microenvironments Matter: Advances in Brain-on-Chip
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13050551
Abstract: To highlight the particular needs with respect to modeling the unique and complex organization of the human brain structure, we reviewed the state-of-the-art in devising brain models with engineered instructive microenvironments. To acquire a better… read more here.
Keywords: advances brain; brain; brain chip; matter advances ... See more keywords