The protective effect of vitamin U on pentylenetetrazole‐induced brain damage in rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23169
Abstract: Pentylenetetrazole (PTZ) is preferred for experimental epilepsy induction. PTZ damages brain and other organs by elevating oxidative substances. Vitamin U (Vit U) is sulfur derivative substance that proved to be an excellent antioxidant. The current… read more here.
Keywords: brain damage; ptz; vit; brain ... See more keywords
Iron overload facilitates neonatal hypoxic–ischemic brain damage via SLC7A11‐mediated ferroptosis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25184
Abstract: Oxidative damage and cell death are involved in the pathogenesis of hypoxic–ischemic brain damage (HIBD). Ferroptosis is a newly identified mode of cell death that results from the oxidative damage induced by excessive iron. In… read more here.
Keywords: brain damage; iron; ferroptosis; hibd ... See more keywords
Neuroprotective effects of icariin in neonatal hypoxia-ischemic brain damage via its anti-apoptotic property
Sign Up to like & getrecommendations! Published in 2020 at "Child's Nervous System"
DOI: 10.1007/s00381-020-04690-8
Abstract: Introduction Neonatal hypoxic-ischemic brain damage (HIBD) is a brain disease that is caused by perinatal asphyxia. Icariin (ICA), which is an active component of Epimedii (a Chinese medicinal herb), has been verified to demonstrate a… read more here.
Keywords: neuroprotective effects; anti apoptotic; brain damage; brain ... See more keywords
Epigallocatechin Gallate Alleviates Down-Regulation of Thioredoxin in Ischemic Brain Damage and Glutamate-Exposed Neuron.
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical research"
DOI: 10.1007/s11064-021-03403-0
Abstract: Epigallocatechin gallate (EGCG) is one of polyphenol that is abundant in green tea. It has anti-oxidative activity and exerts neuroprotective effects in ischemic brain damage. Ischemic conditions induce oxidative stress and result in cell death.… read more here.
Keywords: thioredoxin; glutamate; ischemic brain; brain damage ... See more keywords
Uric Acid Treatment After Stroke Prevents Long-Term Middle Cerebral Artery Remodelling and Attenuates Brain Damage in Spontaneously Hypertensive Rats
Sign Up to like & getrecommendations! Published in 2018 at "Translational Stroke Research"
DOI: 10.1007/s12975-018-0661-8
Abstract: Hypertension is the most important modifiable risk factor for stroke and is associated with poorer post-stroke outcomes. The antioxidant uric acid is protective in experimental normotensive ischaemic stroke. However, it is unknown whether this treatment… read more here.
Keywords: long term; uric acid; brain; brain damage ... See more keywords
Mitochondrial dynamics and protective effects of a mitochondrial division inhibitor, Mdivi-1, in lipopolysaccharide-induced brain damage.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.01.136
Abstract: Sepsis is one of the most common reasons for mortality in Intensive Care Units. As a common but severe neurological complication, sepsis associated encephalopathy (SAE) has always been ignored and there is no generally accepted… read more here.
Keywords: mitochondrial dynamics; brain damage; drp1; inhibitor ... See more keywords
Therapeutic potential of stem cells for preterm infant brain damage: can we move from the heterogeneity of preclinical and clinical studies to established therapeutics?
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114461
Abstract: Acquired perinatal brain injuries are a set of conditions that remains a key challenge for neonatologists and that have significant social, emotional and financial implications for our communities. In our perspective article, will introduce perinatal… read more here.
Keywords: stem cells; perinatal brain; brain; brain damage ... See more keywords
Multiple cytokine analysis in gastroschisis: Association with adverse outcomes including fetal brain damage.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155406
Abstract: OBJECTIVES To investigate the distribution of multiple cytokines in gastroschisis and reveal its association with clinical outcomes, including gastrointestinal disorders and fetal brain damage caused by chronic inflammation in gastroschisis. METHODS We obtained amniotic fluid… read more here.
Keywords: brain damage; cord; adverse outcomes; gastroschisis ... See more keywords
SA33 VARIABILITY IN EXPRESSION OF TMEM163 IN BRAIN CORTEX IS ASSOCIATED WITH RESILIENCE TO MULTIPLE BRAIN DAMAGE PHENOTYPES IN A BIOBANK POPULATION
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.105
Abstract: Background Resilience to brain damage describes the imperfect correlation between clinical symptoms and the extent of brain injury, whether traumatic, degenerative, or vascular in origin. DNA samples linked to electronic medical records (biobanks) offer unique… read more here.
Keywords: resilience; expression; tbi; brain damage ... See more keywords
Oxymatrine protects neonatal rat against hypoxic-ischemic brain damage via PI3K/Akt/GSK3β pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.04.070
Abstract: AIMS In this study we aimed to explore the specific effect and mechanism of oxymatrine on neonatal rats hypoxic-ischemic brain damage. MATERIALS AND METHODS Hypoxia-ischemia damage model was built by ligaturing the left common carotid… read more here.
Keywords: hypoxic ischemic; damage; brain damage; cell ... See more keywords
Sevoflurane improves nerve regeneration and repair of neurological deficit in brain damage rats via microRNA-490-5p/CDK1 axis.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119111
Abstract: BACKGROUND Sevoflurane (Sevo) is neuroprotective in brain damage, thus our objective was to further investigate the impact of Sevo treatment on nerve regeneration and repair of neurological deficit in brain damage rats by regulating miR-490-5p… read more here.
Keywords: mir 490; repair neurological; damage rats; brain damage ... See more keywords