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   Articles with "brain drug" as a keyword



Targeting the transferrin receptor for brain drug delivery

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recommendations! Published in 2019 at "Progress in Neurobiology"

DOI: 10.1016/j.pneurobio.2019.101665

Abstract: Obtaining efficient drug delivery to the brain remains the biggest challenge for the development of therapeutics to treat diseases of the central nervous system. The main obstacle is the blood-brain barrier (BBB), which impedes the… read more here.

Keywords: drug; drug delivery; brain drug; transferrin receptor ... See more keywords

Harnessing Exosomes for the Development of Brain Drug Delivery Systems.

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recommendations! Published in 2019 at "Bioconjugate chemistry"

DOI: 10.1021/acs.bioconjchem.9b00085

Abstract: Brain drug delivery is one of the most important bottlenecks in the development of drugs for the central nervous system. Cumulative evidence has emerged that extracellular vesicles (EVs) play a key role in intercellular communication.… read more here.

Keywords: drug delivery; brain drug; brain; development ... See more keywords
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Stimulating brain drug delivery

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recommendations! Published in 2020 at "Science Translational Medicine"

DOI: 10.1126/scitranslmed.abe8119

Abstract: Neural activity affects how the blood-brain barrier regulates influx and efflux of agents between the blood and the central nervous system. Neural activity affects how the blood-brain barrier regulates influx and efflux of agents between… read more here.

Keywords: medicine; drug delivery; stimulating brain; brain drug ... See more keywords
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Lipid and Polymeric Nanoparticles: Successful Strategies for Nose-to-Brain Drug Delivery in the Treatment of Depression and Anxiety Disorders

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recommendations! Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14122742

Abstract: Intranasal administration has gained an increasing interest for brain drug delivery since it allows direct transport through neuronal pathways, which can be quite advantageous for central nervous system disorders, such as depression and anxiety. Nanoparticles… read more here.

Keywords: brain drug; treatment depression; drug; depression anxiety ... See more keywords