Current technical approaches to brain energy metabolism
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23248
Abstract: Neuroscience is a technology‐driven discipline and brain energy metabolism is no exception. Once satisfied with mapping metabolic pathways at organ level, we are now looking to learn what it is exactly that metabolic enzymes and… read more here.
Keywords: brain energy; energy metabolism; brain; biology ... See more keywords
Neuron‐glia (mis)interactions in brain energy metabolism during aging
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25015
Abstract: Life expectancy in humans is increasing, resulting in a growing aging population, that is accompanied by an increased disposition to develop cognitive deterioration. Hypometabolism is one of the multiple factors related to inefficient brain function… read more here.
Keywords: mis interactions; interactions brain; glia mis; neuron glia ... See more keywords
Alterations of Brain Energy Metabolism in Type 2 Diabetic Goto-Kakizaki Rats Measured In Vivo by 13C Magnetic Resonance Spectroscopy
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicity Research"
DOI: 10.1007/s12640-017-9821-y
Abstract: Type 2 diabetes (T2D) is associated with deterioration of brain structure and function. Here, we tested the hypothesis that T2D induces a reorganization of the brain metabolic networks that support brain function. For that, alterations… read more here.
Keywords: brain energy; energy metabolism; brain; spectroscopy ... See more keywords
Control of brain energy supply by astrocytes
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2017.09.012
Abstract: Astrocytes form an anatomical bridge between the vasculature and neuronal synapses. Recent work suggests that they play a key role in regulating brain energy supply by increasing blood flow to regions where neurons are active,… read more here.
Keywords: control brain; brain energy; energy supply; energy ... See more keywords
Possible Clues for Brain Energy Translation via Endolysosomal Trafficking of APP-CTFs in Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/2764831
Abstract: Vascular dysfunctions, hypometabolism, and insulin resistance are high and early risk factors for Alzheimer's disease (AD), a leading neurological disease associated with memory decline and cognitive dysfunctions. Early defects in glucose transporters and glycolysis occur… read more here.
Keywords: brain energy; energy; ctfs; alzheimer disease ... See more keywords
Brain Energy Metabolism in Two States of Mind Measured by Phosphorous Magnetic Resonance Spectroscopy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Human Neuroscience"
DOI: 10.3389/fnhum.2021.686433
Abstract: Introduction: Various functional neuroimaging studies help to better understand the changes in brain activity during meditation. The purpose of this study was to investigate how brain energy metabolism changes during focused attention meditation (FAM) state,… read more here.
Keywords: state; brain energy; spectroscopy; energy metabolism ... See more keywords
Brain’s Energy After Stroke: From a Cellular Perspective Toward Behavior
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Integrative Neuroscience"
DOI: 10.3389/fnint.2022.826728
Abstract: Stroke is a neurological condition that impacts activity performance and quality of life for survivors. While neurological impairments after the event explain the performance of patients in specific activities, the origin of such impairments has… read more here.
Keywords: brain energy; energy stroke; energy; stroke cellular ... See more keywords
Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.825816
Abstract: Astrocytes play key roles in the regulation of brain energy metabolism, which has a major impact on brain functions, including memory, neuroprotection, resistance to oxidative stress and homeostatic tone. Energy demands of the brain are… read more here.
Keywords: energy; energy metabolism; new therapeutic; brain ... See more keywords
Synapses: The Brain’s Energy-Demanding Sites
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073627
Abstract: The brain is one of the most energy-consuming organs in the mammalian body, and synaptic transmission is one of the major contributors. To meet these energetic requirements, the brain primarily uses glucose, which can be… read more here.
Keywords: demanding sites; energy demanding; brain energy; energy ... See more keywords
Nutrients to Improve Mitochondrial Function to Reduce Brain Energy Deficit and Oxidative Stress in Migraine
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13124433
Abstract: The mechanisms of migraine pathogenesis are not completely clear, but 31P-nuclear magnetic resonance studies revealed brain energy deficit in migraineurs. As glycolysis is the main process of energy production in the brain, mitochondria may play… read more here.
Keywords: energy; energy deficit; migraine; oxidative stress ... See more keywords