Abstinence following intermittent methylphenidate exposure dose‐dependently modifies brain glucose metabolism in the rat brain
Sign Up to like & getrecommendations! Published in 2022 at "Synapse"
DOI: 10.1002/syn.22243
Abstract: Methylphenidate (MP) is a psychostimulant chronically prescribed for the treatment of attention deficit hyperactivity disorder (ADHD). Additionally, MP users may take breaks from using the medication during “drug holidays,” which may include short‐term or long‐term… read more here.
Keywords: brain glucose; abstinence; brain; glucose metabolism ... See more keywords
Measurement of brain glucose metabolism in obesity and diabetes
Sign Up to like & getrecommendations! Published in 2025 at "Diabetologia"
DOI: 10.1007/s00125-025-06491-7
Abstract: The brain consumes a large amount of glucose to fuel its high metabolic demands. Understanding brain glucose metabolism is critical for understanding the brain’s normal physiology and the pathological states of diabetes and obesity. However,… read more here.
Keywords: brain glucose; brain; glucose metabolism; obesity ... See more keywords
The beneficial effect of exercise against Alzheimer's disease may result from improved brain glucose metabolism
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.136182
Abstract: The potential of physical exercise as an intervention for Alzheimer's disease (AD) has been extensively reported. In fact, a number of studies have highlighted improvements in β-amyloid (Aβ) peptide and hyperphosphorylated tau (p-tau) as critical… read more here.
Keywords: exercise; glucose metabolism; disease; brain glucose ... See more keywords
Effects of lead exposure on brain glucose metabolism and insulin signaling pathway in the hippocampus of rats.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.04.011
Abstract: The aim of this study was to determine whether Pb affects glucose metabolism in the hippocampus of rats. Male Sprague-Dawley rats aged 21 days were orally administered a 0.1%, 0.2%, or 0.3% lead acetate solution… read more here.
Keywords: brain glucose; signaling pathway; glucose metabolism; brain ... See more keywords
Brain glucose metabolism in schizophrenia: a systematic review and meta-analysis of 18FDG-PET studies in schizophrenia.
Sign Up to like & getrecommendations! Published in 2022 at "Psychological medicine"
DOI: 10.1017/s003329172200174x
Abstract: BACKGROUND Impaired brain metabolism may be central to schizophrenia pathophysiology, but the magnitude and consistency of metabolic dysfunction is unknown. METHODS We searched MEDLINE, PsychINFO and EMBASE between 01/01/1980 and 13/05/2021 for studies comparing regional… read more here.
Keywords: metabolism; brain glucose; 18fdg pet; glucose metabolism ... See more keywords
Brain Glucose Metabolism as a Readout of the Central Nervous System Impact of Cigarette Smoke Exposure and Withdrawal and the Effects of NFL-101, as an Immune-Based Drug Candidate for Smoking Cessation Therapy.
Sign Up to like & getrecommendations! Published in 2024 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.4c00204
Abstract: Neuroimaging biomarkers are needed to investigate the impact of smoking withdrawal on brain function. NFL-101 is a denicotinized aqueous extract of tobacco leaves currently investigated as an immune-based smoking cessation therapy in humans. However, the… read more here.
Keywords: brain glucose; brain; glucose metabolism; withdrawal ... See more keywords
Brain glucose metabolism and gray matter volume in retired professional soccer players: a cross-sectional [ 18 F]FDG-PET/MRI study
Sign Up to like & getrecommendations! Published in 2022 at "Arquivos de Neuro-Psiquiatria"
DOI: 10.1055/s-0043-1768666
Abstract: Abstract Background Professional soccer athletes are exposed to repetitive head impacts and are at risk of developing chronic traumatic encephalopathy. Objective To evaluate regional brain glucose metabolism (rBGM) and gray matter (GM) volume in retired… read more here.
Keywords: soccer players; brain glucose; soccer; volume ... See more keywords
Brain Glucose Metabolism in Parry-Romberg Syndrome.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000001558
Abstract: Parry-Romberg syndrome is a rare disorder characterized by a progressive facial hemiatrophy of the skin, subcutaneous tissue, musculature, bone, and cartilage. It is often associated with neurological symptoms such as trigeminal neuropathy, paresthesia of the… read more here.
Keywords: parry romberg; romberg syndrome; metabolism parry; glucose metabolism ... See more keywords
Blunted rise in brain glucose levels during hyperglycemia in adults with obesity and T2DM.
Sign Up to like & getrecommendations! Published in 2017 at "JCI insight"
DOI: 10.1172/jci.insight.95913
Abstract: In rodent models, obesity and hyperglycemia alter cerebral glucose metabolism and glucose transport into the brain, resulting in disordered cerebral function as well as inappropriate responses to homeostatic and hedonic inputs. Whether similar findings are… read more here.
Keywords: glucose levels; brain glucose; obesity t2dm; obesity ... See more keywords
Effect of Chinese herbal compound GAPT on the early brain glucose metabolism of APP/PS1 transgenic mice
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/2058738419841482
Abstract: A number of studies have shown that early-stage Alzheimer’s disease (AD) is associated with abnormal brain glucose metabolism before cognitive decline, which may be the key pathological change of asymptomatic AD. The pathogenesis of AD… read more here.
Keywords: brain glucose; transgenic mice; glucose metabolism; app ps1 ... See more keywords
Glucose-Sparing Action of Ketones Boosts Functions Exclusive to Glucose in the Brain
Sign Up to like & getrecommendations! Published in 2020 at "eNeuro"
DOI: 10.1523/eneuro.0303-20.2020
Abstract: Abstract The ketogenic diet (KD) has been successfully used for a century for treating refractory epilepsy and is currently seen as one of the few viable approaches to the treatment of a plethora of metabolic… read more here.
Keywords: action ketones; brain glucose; ketone bodies; glucose sparing ... See more keywords