Trajectories of Insomnia in Adults After Traumatic Brain Injury
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DOI: 10.1001/jamanetworkopen.2021.45310
Abstract: Key Points Question What is the natural history of insomnia in the 12 months after traumatic brain injury (TBI)? Findings In this analysis of 2022 adults from the large cohort study Transforming Research and Clinical… read more here.
Keywords: insomnia adults; trajectories insomnia; traumatic brain; brain injury ... See more keywords
Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury
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DOI: 10.1001/jamanetworkopen.2022.0891
Abstract: Key Points Question How commonly are hyperosmolar therapies used in the management of severe traumatic brain injury in children, and which agent—mannitol or hypertonic saline solution—is associated with greater decreases in intracranial pressure (ICP) and/or… read more here.
Keywords: traumatic brain; mannitol; brain injury; hypertonic saline ... See more keywords
Association of Traumatic Brain Injury With and Without Loss of Consciousness With Neuropathologic Outcomes in Community-Dwelling Older Persons
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DOI: 10.1001/jamanetworkopen.2022.9311
Abstract: Key Points Question Is traumatic brain injury (TBI) with and without loss of consciousness (LOC) associated with dementia-related neuropathologic outcomes in older persons? Findings In this cross-sectional analysis of 1689 autopsied participants from 3 community-based… read more here.
Keywords: traumatic brain; without loss; older persons; brain injury ... See more keywords
Association of Traumatic Brain Injury With the Risk of Developing Chronic Cardiovascular, Endocrine, Neurological, and Psychiatric Disorders
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DOI: 10.1001/jamanetworkopen.2022.9478
Abstract: Key Points Question Is traumatic brain injury associated with long-term risk of cardiometabolic, neurological, or psychiatric comorbidities? Findings In this cohort study including 4351 patients each with mild or moderate to severe TBI and 4351… read more here.
Keywords: cardiovascular endocrine; traumatic brain; risk; brain injury ... See more keywords
Functional Recovery, Symptoms, and Quality of Life 1 to 5 Years After Traumatic Brain Injury
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DOI: 10.1001/jamanetworkopen.2023.3660
Abstract: Key Points Question What is the course of functional, symptom, and quality of life outcomes 1 to 5 years after mild traumatic brain injury (mTBI) and moderate-severe traumatic brain injury (msTBI)? Findings In this cohort… read more here.
Keywords: traumatic brain; quality life; brain injury;
Interventions to Reduce Severe Brain Injury Risk in Preterm Neonates
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DOI: 10.1001/jamanetworkopen.2023.7473
Abstract: This systematic review and meta-analysis examines the role of perinatal interventions in the development of severe intraventricular hemorrhage and cystic periventricular leukomalacia in neonates born before 37 weeks’ gestation. read more here.
Keywords: risk preterm; interventions reduce; injury risk; reduce severe ... See more keywords
Identification of Palliative Care Needs and Mental Health Outcomes Among Family Members of Patients With Severe Acute Brain Injury
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DOI: 10.1001/jamanetworkopen.2023.9949
Abstract: Importance Family members of patients with severe acute brain injury (SABI) are at risk for poor psychological outcomes. Objective To explore the utility of the early use of a palliative care needs checklist in identifying… read more here.
Keywords: family; family members; palliative care; brain injury ... See more keywords
Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2019.1313
Abstract: Importance Most traumatic brain injuries (TBIs) are classified as mild (mTBI) based on admission Glasgow Coma Scale (GCS) scores of 13 to 15. The prevalence of persistent functional limitations for these patients is unclear. Objectives… read more here.
Keywords: traumatic brain; level trauma; group; brain injury ... See more keywords
Association Between Traumatic Brain Injury and Subsequent Cardiovascular Disease Among Post-9/11–Era Veterans
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DOI: 10.1001/jamaneurol.2022.2682
Abstract: This cohort study investigates the association of traumatic brain injury with subsequent risk of cardiovascular disease in veterans of the recent conflicts in Iraq and Afghanistan. read more here.
Keywords: traumatic brain; association traumatic; cardiovascular disease; injury subsequent ... See more keywords
Dexmedetomidine Attenuates Neuroinflammatory–Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50878
Abstract: Dexmedetomidine (DEX) exhibits neuroprotective effects as a multifunctional neuroprotective agent in numerous neurological disorders. However, in traumatic brain injury (TBI), the molecular mechanisms of these neuroprotective effects remain unclear. The present study investigated whether DEX,… read more here.
Keywords: neuroinflammatory induced; brain injury; traumatic brain; induced apoptosis ... See more keywords
Network diffusion modeling predicts neurodegeneration in traumatic brain injury
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DOI: 10.1002/acn3.50984
Abstract: Traumatic brain injury (TBI) is a heterogeneous disease with multiple neurological deficits that evolve over time. It is also associated with an increased incidence of neurodegenerative diseases. Accordingly, clinicians need better tools to predict a… read more here.
Keywords: diffusion modeling; brain injury; traumatic brain; network diffusion ... See more keywords