Tau in the brain interstitial fluid is fragmented and seeding–competent
Sign Up to like & getrecommendations! Published in 2022 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.09.013
Abstract: In Alzheimer disease, Tau pathology is thought to propagate from cell to cell throughout interconnected brain areas. However, the forms of Tau released into the brain interstitial fluid (ISF) in vivo during the development of… read more here.
Keywords: tau; brain interstitial; seeding competent; interstitial fluid ... See more keywords
Platform for micro-invasive membrane-free biochemical sampling of brain interstitial fluid
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DOI: 10.1126/sciadv.abb0657
Abstract: Micro-invasive platform performs label-free liquid biopsies of the brain, enabling in vivo tracking of proteins and peptides. Neurochemical dysregulation underlies many pathologies and can be monitored by measuring the composition of brain interstitial fluid (ISF).… read more here.
Keywords: brain interstitial; micro invasive; interstitial fluid; platform ... See more keywords
Epidural Pulsation Accelerates the Drainage of Brain Interstitial Fluid
Sign Up to like & getrecommendations! Published in 2023 at "Aging and Disease"
DOI: 10.14336/ad.2022.0609
Abstract: Unhindered transportation of substances in the brain extracellular space (ECS) is essential for maintaining brain function. Regulation of transportation is a novel strategy for treating ECS blockage-related brain diseases, but few techniques have been developed… read more here.
Keywords: drainage; brain interstitial; pulsation; brain ... See more keywords