Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence
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DOI: 10.1007/s11357-017-9964-z
Abstract: Whole brain irradiation (WBI) is a mainstream therapy for patients with both identifiable brain metastases and prophylaxis for microscopic malignancies. However, it also promotes accelerated senescence in healthy tissues and leads to progressive cognitive dysfunction… read more here.
Keywords: irradiation; irradiation induced; whole brain; brain ... See more keywords
Accelerated or conventional whole brain irradiation of malignant melanoma
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DOI: 10.1080/0284186x.2016.1275777
Abstract: Ragnar Hultborn, Johanna Sand, Sara Kinhult, Lotta Lundgren, Ulrika Stierner, Ingela Turesson and Per Albertsson Department of Oncology, Sahlgrenska Academy, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Oncology, Skane University Hospital, Lund, Sweden; Department of… read more here.
Keywords: oncology; whole brain; irradiation malignant; conventional whole ... See more keywords
Ameliorative effect of black grape juice on systemic alterations and mandibular osteoradionecrosis induced by whole brain irradiation in rats
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DOI: 10.1080/09553002.2017.1231945
Abstract: Abstract Purpose: Whole brain irradiation (WBI) causes a variety of secondary side-effects including anorexia and bone necrosis. We evaluated the radiomodifying effect of black grape juice (BGJ) on WBI alterations in rats measuring food and… read more here.
Keywords: irradiation; black grape; brain irradiation; effect black ... See more keywords
SMART syndrome: two cases highlighting a complex and rare complication of brain irradiation
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DOI: 10.1136/bcr-2022-249599
Abstract: Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare complication of radiotherapy with complex neurological impairment. Patients present with neurological symptoms and signs such as migraine, hemianopsia, hemiplegia, aphasia and/or seizures—without recurrence of… read more here.
Keywords: syndrome two; brain irradiation; rare complication; smart syndrome ... See more keywords
Rescue of cognitive function following fractionated brain irradiation in a novel preclinical glioma model
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DOI: 10.7554/elife.38865
Abstract: More than half of long-term brain tumor survivors develop irreversible cognitive decline that severely affect their quality of life. However, there is no pre-clinical model that allows long-term assessment of cognition, and there is no… read more here.
Keywords: glioma; rescue cognitive; model; brain ... See more keywords