Curcumin and Homotaurine Suppress Amyloid-β25-35 Aggregation in Synthetic Brain Membranes.
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DOI: 10.1021/acschemneuro.1c00057
Abstract: Amyloid-β (Aβ) peptides spontaneously aggregate into β- and cross-β-sheets in model brain membranes. These nanometer sized can fuse into larger micrometer sized clusters and become extracellular and serve as nuclei for further plaque and fibril… read more here.
Keywords: aggregation; brain membranes; synthetic brain; curcumin homotaurine ... See more keywords