Carotid foramen size in the human skull tracks developmental changes in cerebral blood flow and brain metabolism.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.23809
Abstract: OBJECTIVES In humans, neuronal processes related to brain development elevate the metabolic rate of brain tissue relative to the body during early childhood. This phenomenon has been hypothesized to contribute to slow somatic growth in… read more here.
Keywords: blood flow; size; brain metabolism; brain ... See more keywords
Proton magnetic resonance spectroscopy assessment of neonatal brain metabolism during cardiopulmonary bypass surgery
Sign Up to like & getrecommendations! Published in 2022 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4752
Abstract: Here, we report on the development and performance of a robust 3‐T single‐voxel proton magnetic resonance spectroscopy (1H MRS) experimental protocol and data analysis pipeline for quantifying brain metabolism during cardiopulmonary bypass (CPB) surgery in… read more here.
Keywords: surgery; spectroscopy; brain; proton magnetic ... See more keywords
Brain [11C]PK11195 and [18F]FDG PET imaging in a rat model of postoperative cognitive dysfunction
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3822-1
Abstract: Aim: Postoperative cognitive dysfunction (POCD) is a common complication after surgery that can have a long-lasting negative impact on the patient’s quality of life. Although the underlying mechanism is still unknown, evidence suggests that neuroinflammation… read more here.
Keywords: surgery; pet; metabolism; neuroinflammation ... See more keywords
Brain metabolism and severe pediatric traumatic brain injury
Sign Up to like & getrecommendations! Published in 2017 at "Child's Nervous System"
DOI: 10.1007/s00381-017-3514-y
Abstract: Age-dependent changes in brain metabolism may influence the response to and tolerance of secondary insults, potentially affecting outcomes. More complete characterization of brain metabolism across the clinical trajectory of severe pediatric TBI is needed to… read more here.
Keywords: secondary insults; brain metabolism; metabolism severe; severe pediatric ... See more keywords
Predicting Alzheimer's disease with practice effects, APOE genotype and brain metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.12.011
Abstract: After the paper Cognition or genetics. Predicting progression to Alzheimer's disease with practice effects, APOE genotype and brain metabolism [Neurobiol Aging, 2018; 71:234-240] was published, we identified a coding error of one of the variables… read more here.
Keywords: brain metabolism; rcirb; practice effects; practice ... See more keywords
Incorporation of anatomical MRI knowledge for enhanced mapping of brain metabolism using functional PET
Sign Up to like & getrecommendations! Published in 2021 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2021.117928
Abstract: Functional positron emission tomography (fPET) imaging using continuous infusion of [18F]-fluorodeoxyglucose (FDG) is a novel neuroimaging technique to track dynamic glucose utilization in the brain. In comparison to conventional static or dynamic bolus PET, fPET… read more here.
Keywords: functional pet; brain; fpet; brain metabolism ... See more keywords
Fluorodeoxyglucose Detected Changes in Brain Metabolism After Chemotherapy in Pediatric Non-Hodgkin Lymphoma.
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric neurology"
DOI: 10.1016/j.pediatrneurol.2018.10.019
Abstract: BACKGROUND Potential neurocognitive dysfunction after chemotherapy is a worrisome long-term outcome. Our objective was to evaluate the effect on brain metabolism in pediatric patients with non-central nervous system cancer treated with chemotherapy by analyzing brain… read more here.
Keywords: chemotherapy; brain metabolism; brain; metabolism chemotherapy ... See more keywords
Exercise Alleviates Behavioral Disorders but Shapes Brain Metabolism of APP/PS1 Mice in a Region- and Exercise-Specific Manner.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00691
Abstract: Exercise plays a beneficial role in the management of Alzheimer's disease (AD), but its effects on brain metabolism are still far from being understood. Here, we examined behavioral changes of APP/PS1 mice after high-intensity interval… read more here.
Keywords: metabolism; app ps1; exercise; ps1 mice ... See more keywords
Real-time ex-vivo measurement of brain metabolism using hyperpolarized [1-13C]pyruvate
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27747-w
Abstract: The ability to directly monitor in vivo brain metabolism in real time in a matter of seconds using the dissolution dynamic nuclear polarization technology holds promise to aid the understanding of brain physiology in health… read more here.
Keywords: real time; metabolism; 13c pyruvate; hyperpolarized 13c ... See more keywords
Normal brain metabolism on FDG PET/MRI during childhood and adolescence
Sign Up to like & getrecommendations! Published in 2018 at "Nuclear Medicine Communications"
DOI: 10.1097/mnm.0000000000000912
Abstract: Objective The aim was to investigate normal patterns of brain metabolism determined by 18F-fluorodeoxyglucose positron emission tomography (FDG PET)/MRI during childhood and adolescence. Patients and methods A retrospective analysis was carried out on all paediatric… read more here.
Keywords: adolescence; fdg pet; brain; brain metabolism ... See more keywords
MeCP2 Is an Epigenetic Factor That Links DNA Methylation with Brain Metabolism
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24044218
Abstract: DNA methylation, one of the most well-studied epigenetic modifications, is involved in a wide spectrum of biological processes. Epigenetic mechanisms control cellular morphology and function. Such regulatory mechanisms involve histone modifications, chromatin remodeling, DNA methylation,… read more here.
Keywords: methylation; dna methylation; brain metabolism;