An in vitro hyaluronic acid hydrogel based platform to model dormancy in brain metastatic breast cancer cells.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.02.039
Abstract: Breast cancer cells (BCCs) can remain dormant at the metastatic site, which when revoked leads to formation of metastasis several years after the treatment of primary tumor. Particularly, awakening of dormant BCCs in the brain… read more here.
Keywords: hydrogel; dormancy; breast cancer; model dormancy ... See more keywords
Structure Reconstruction of LyP-1: Lc(LyP-1) Coupling by Amide Bond Inspires the Brain Metastatic Tumor Targeted Drug Delivery.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00801
Abstract: The stability and binding affinity of targeting ligands are very important in active targeting drug delivery. Herein we used LyP-1 peptide as a model peptide to investigate chemical-biology-based strategies in the design of peptide ligands… read more here.
Keywords: lyp; drug delivery; metastatic tumor; brain metastatic ... See more keywords
A nomogram for predicting overall survival rate in patients with brain metastatic non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030824
Abstract: The purpose was to develop a nomogram for the prediction of the 1- and 2-year overall survival (OS) rates in patients with brain metastatic non-small cell lung cancer (BMNSCLC). Patients were collected from the Surveillance… read more here.
Keywords: brain metastatic; non small; metastatic non; patients brain ... See more keywords
GAD1 Upregulation Programs Aggressive Features of Cancer Cell Metabolism in the Brain Metastatic Microenvironment.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-16-2289
Abstract: The impact of altered amino acid metabolism on cancer progression is not fully understood. We hypothesized that a metabolic transcriptome shift during metastatic evolution is crucial for brain metastasis. Here, we report a powerful impact… read more here.
Keywords: gad1; metabolism; upregulation; cancer ... See more keywords
Therapeutic Effectiveness of Immunoradiotherapy on Brain-metastatic BRAF/MEK Inhibitor-resistant Melanoma with Balloon Cell Change.
Sign Up to like & getrecommendations! Published in 2019 at "Acta dermato-venereologica"
DOI: 10.2340/00015555-3134
Abstract: 1https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3134 Balloon cell malignant melanoma (BCMM) is a rare variant of melanoma, first reported by Gardner & Vasquez in 1970 (1). BCMM is histologically characterized by large and polyhedral foamy cells with abundant cytoplasmic vacuoles… read more here.
Keywords: melanoma; braf mek; balloon cell; brain metastatic ... See more keywords
The Importance of Small Extracellular Vesicles in the Cerebral Metastatic Process
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031449
Abstract: Brain metastases represent more than 50% of all cerebral tumors encountered in clinical practice. Recently, there has been increased interest in the study of extracellular vesicles, and the knowledge about exosomes is constantly expanding. Exosomes… read more here.
Keywords: importance small; brain metastatic; extracellular vesicles; metastatic process ... See more keywords