Effect of Novel Antipsychotics on Energy Metabolism - In Vitro Study in Pig Brain Mitochondria.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02498-4
Abstract: The identification and quantification of mitochondrial effects of novel antipsychotics (brexpiprazole, cariprazine, loxapine, and lurasidone) were studied in vitro in pig brain mitochondria. Selected parameters of mitochondrial metabolism, electron transport chain (ETC) complexes, citrate synthase… read more here.
Keywords: production; loxapine; pig brain; novel antipsychotics ... See more keywords
Attenuation of brain mitochondria oxidative damage by Albizia julibrissin Durazz: neuroprotective and antiemetic effects
Sign Up to like & getrecommendations! Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2017.1413106
Abstract: Abstract Medicinal plants, as new drugs, are considered for treatment of insomnia, anxiety, depression, confusion, nausea, and vomiting symptoms. The current study aimed to evaluate the neuroprotective and antiemetic effects of Albizia. julibrissin Durazz. flower… read more here.
Keywords: brain mitochondria; emesis; emesis induced; copper sulfate ... See more keywords
The role of exerkines on brain mitochondria: a mini-review.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00565.2022
Abstract: Exercise benefits many organ systems, including having a panacea-like effect on the brain. For example, aerobic exercise improves cognition and attention and reduces the risk of brain-related diseases, such as dementia, stress, and depression. Recent… read more here.
Keywords: role exerkines; exerkines brain; brain mitochondria; review ... See more keywords
Naked mole rat brain mitochondria electron transport system flux and H+ leak are reduced during acute hypoxia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Experimental Biology"
DOI: 10.1242/jeb.171397
Abstract: ABSTRACT Mitochondrial respiration and ATP production are compromised by hypoxia. Naked mole rats (NMRs) are among the most hypoxia-tolerant mammals and reduce metabolic rate in hypoxic environments; however, little is known regarding mitochondrial function during… read more here.
Keywords: hypoxia; acute hypoxia; naked mole; brain mitochondria ... See more keywords
Brain Mitochondria as a Therapeutic Target for Carnosic Acid.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2303053
Abstract: Carnosic acid (CA), a diterpene obtained mainly from Rosmarinus officinalis and Salvia officinalis, exerts antioxidant, anti-inflammatory, and anti-apoptotic effects in mammalian cells. At least in part, those benefits are associated with the ability that CA… read more here.
Keywords: carnosic acid; brain; brain mitochondria; mitochondria therapeutic ... See more keywords
Acidosis Maintains the Function of Brain Mitochondria in Hypoxia-Tolerant Triplefin Fish: A Strategy to Survive Acute Hypoxic Exposure?
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.01941
Abstract: The vertebrate brain is generally very sensitive to acidosis, so a hypoxia-induced decrease in pH is likely to have an effect on brain mitochondria (mt). Mitochondrial respiration (JO2) is required to generate an electrical gradient… read more here.
Keywords: acidosis; triplefin fish; atp synthesis; brain mitochondria ... See more keywords