Neuroimaging-based brain-age prediction in diverse forms of epilepsy: a signature of psychosis and beyond
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Psychiatry"
DOI: 10.1038/s41380-019-0446-9
Abstract: Epilepsy is a diverse brain disorder, and the pathophysiology of its various forms and comorbidities is largely unknown. A recent machine learning method enables us to estimate an individual’s “brain-age” from MRI; this brain-age prediction… read more here.
Keywords: age; brain age; age prediction; brain ... See more keywords
Contributing factors to advanced brain aging in depression and anxiety disorders
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01524-2
Abstract: Depression and anxiety are common and often comorbid mental health disorders that represent risk factors for aging-related conditions. Brain aging has shown to be more advanced in patients with major depressive disorder (MDD). Here, we… read more here.
Keywords: anxiety; brain; brain pad; depression anxiety ... See more keywords
Health-related heterogeneity in brain aging and associations with longitudinal change in cognitive function
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.1063721
Abstract: Introduction Neuroimaging-based ‘brain age’ can identify individuals with ‘advanced’ or ‘resilient’ brain aging. Brain-predicted age difference (brain-PAD) is predictive of cognitive and physical health outcomes. However, it is unknown how individual health and lifestyle factors… read more here.
Keywords: health; brain aging; class; brain ... See more keywords
Worse Physical Disability Is Associated With the Expression of PD-1 on Inflammatory T-Cells in Multiple Sclerosis Patients With Older Appearing Brains
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2021.801097
Abstract: Background: Magnetic Resonance Imaging (MRI) analysis method “brain-age” paradigm could offer an intuitive prognostic metric (brain-predicted age difference: brain-PAD) for disability in Multiple Sclerosis (MS), reflecting structural brain health adjusted for aging. Equally, cellular senescence… read more here.
Keywords: disability; brain pad; brain; age ... See more keywords
Peripheral inflammation levels associated with degree of advanced brain aging in schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.966439
Abstract: Brain structural abnormalities have been demonstrated in schizophrenia (SZ); these resemble those seen in typical aging, but are seen at younger ages. Furthermore, SZ is associated with accelerated global brain aging, as measured by brain… read more here.
Keywords: brain aging; brain pad; peripheral inflammation; brain ... See more keywords