Precise Ultrasound Neuromodulation in a Deep Brain Region Using Nano Gas Vesicles as Actuators.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced science"
DOI: 10.1002/advs.202101934
Abstract: Ultrasound is a promising new modality for non-invasive neuromodulation. Applied transcranially, it can be focused down to the millimeter or centimeter range. The ability to improve the treatment's spatial resolution to a targeted brain region… read more here.
Keywords: brain; brain region; neuromodulation; gas vesicles ... See more keywords
Cdk5 Contributes to Huntington’s Disease Learning and Memory Deficits via Modulation of Brain Region-Specific Substrates
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0828-4
Abstract: Cognitive deficits are a major hallmark of Huntington’s disease (HD) with a great impact on the quality of patient’s life. Gaining a better understanding of the molecular mechanisms underlying learning and memory impairments in HD… read more here.
Keywords: brain region; memory; learning memory; cdk5 ... See more keywords
Synaptic protein interaction networks encode experience by assuming stimulus-specific and brain-region-specific states
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.110076
Abstract: SUMMARY A core network of widely expressed proteins within the glutamatergic post-synapse mediates activity-dependent synaptic plasticity throughout the brain, but the specific proteomic composition of synapses differs between brain regions. Here, we address the question,… read more here.
Keywords: brain region; stimulus specific; interaction networks; protein interaction ... See more keywords
A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.04.014
Abstract: Intimate communication between neural and vascular cells is critical for normal brain development and function. Germinal matrix (GM), a key primordium for the brain reward circuitry, is unique among brain regions for its distinct pace… read more here.
Keywords: specific neural; region specific; brain; brain region ... See more keywords
Integrative Analysis of Genomic And Neuroimaging Data Reveal A Genetic-Brain Region Pathway Regulating Schizophrenia
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.384
Abstract: Abstract Background Schizophrenia (SCZ) is one of the most chronically disabling psychiatric illnesses with a global median lifetime morbid risk of 7.2/1000 persons. Both genetic and brain region pathways were identified as causal regulating tunnels… read more here.
Keywords: genetic brain; analysis; genomic neuroimaging; brain region ... See more keywords
Sex‐ and brain region‐ specific effects of prenatal stress and lead exposure on permissive and repressive post‐translational histone modifications from embryonic development through adulthood
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2017.07.002
Abstract: HIGHLIGHTSGlobal PTHM levels change during normal brain development in mice.Early life Pb ± PS altered the developmental trajectory of PTHM levels.Exposure specific (Pb or PS or Pb + PS) alterations in PTHM levels were observed.Changes… read more here.
Keywords: pthm levels; brain; sex brain; brain region ... See more keywords
A genome-wide pathway enrichment analysis identifies brain region related biological pathways associated with intelligence
Sign Up to like & getrecommendations! Published in 2018 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2018.07.029
Abstract: Intelligence is an important quantitative trait associated with human cognitive ability. The genetic basis of intelligence remains unclear now. Utilizing the latest chromosomal enhancer maps of brain regions, we explored brain region related biological pathways… read more here.
Keywords: intelligence; biological pathways; brain regions; brain region ... See more keywords
Prairie Voles as a Model for Understanding the Genetic and Epigenetic Regulation of Attachment Behaviors.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.7b00475
Abstract: Over a lifetime, humans build relationships with family, friends, and partners that are critically important for our mental and physical health. Unlike commonly used laboratory mice and rats, Microtine rodents provide a unique model to… read more here.
Keywords: prairie voles; region specific; brain region; genetic epigenetic ... See more keywords
Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors
Sign Up to like & getrecommendations! Published in 2018 at "Translational Psychiatry"
DOI: 10.1038/s41398-018-0142-6
Abstract: We previously reported a new line of Shank3 mutant mice which led to a complete loss of Shank3 by deleting exons 4−22 (Δe4−22) globally. Δe4−22 mice display robust ASD-like behaviors including impaired social interaction and… read more here.
Keywords: autism related; related behaviors; brain region; mice ... See more keywords
Generation and assembly of human brain region–specific three-dimensional cultures
Sign Up to like & getrecommendations! Published in 2018 at "Nature Protocols"
DOI: 10.1038/s41596-018-0032-7
Abstract: The ability to generate region-specific three-dimensional (3D) models to study human brain development offers great promise for understanding the nervous system in both healthy individuals and patients. In this protocol, we describe how to generate… read more here.
Keywords: specific three; region specific; brain region; forebrain ... See more keywords
Divergence in brain size and brain region volumes across wild guppy populations
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the Royal Society B: Biological Sciences"
DOI: 10.1098/rspb.2021.2784
Abstract: Complex evolutionary dynamics have produced extensive variation in brain anatomy in the animal world. In guppies, Poecilia reticulata, brain size and anatomy have been extensively studied in the laboratory contributing to our understanding of brain… read more here.
Keywords: size brain; brain; brain size; anatomy ... See more keywords