A dose-response relationship study of hypertonic saline on brain relaxation during supratentorial brain tumour craniotomy
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DOI: 10.1080/02688697.2018.1508640
Abstract: Abstract Background: A prospective, randomized, double-blind study was designed to assess differences in brain relaxation between 2 doses of 3% HS during elective supratentorial brain tumour surgery. Methods: 60 patients undergoing supratentorial craniotomy for tumour… read more here.
Keywords: supratentorial brain; brain tumour; study; brain ... See more keywords
Mannitol Improves Intraoperative Brain Relaxation in Patients With a Midline Shift Undergoing Supratentorial Tumor Surgery: A Randomized Controlled Trial
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DOI: 10.1097/ana.0000000000000585
Abstract: Supplemental Digital Content is available in the text. Background: Mannitol is widely used to reduce brain tissue swelling and improve brain relaxation during neurosurgery. However, the optimal dosage for patients with midline shift undergoing supratentorial… read more here.
Keywords: mannitol; brain relaxation; midline shift; tumor ... See more keywords
Evaluation of continuous intravenous lidocaine on brain relaxation, intraoperative opioid consumption, and surgeon’s satisfaction in adult patients undergoing craniotomy tumor surgery: A randomized controlled trial
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DOI: 10.1097/md.0000000000030227
Abstract: Background: In craniotomy tumor removal, brain relaxation after dura opening is essential. Lidocaine is known to have analgesic and antiinflammatory effects. It is excellent in decreasing cerebral metabolic rate of oxygen, cerebral blood flow, and… read more here.
Keywords: surgeon satisfaction; brain relaxation; craniotomy tumor; brain ... See more keywords
Equiosmolar hypertonic saline and mannitol for brain relaxation in patients undergoing supratentorial tumor surgery: A systematic review and meta-analysis
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DOI: 10.25259/sni_136_2022
Abstract: Background: Hypertonic saline (HS) and mannitol are hyperosmolar agents that are usually used to reduce intracranial pressure (ICP) and provide a satisfactory brain relaxation. The aim of the study was to perform a systematic review… read more here.
Keywords: review meta; brain relaxation; brain; systematic review ... See more keywords
A summary of some of the recently published, seminal papers in neuroscience.
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DOI: 10.4103/0028-3886.263220
Abstract: In this randomized, controlled double-blinded study, 204 patients with preoperative midline shift undergoing elective supratentorial brain tumor surgery were equally allocated to receive placebo or 0.7, 1.0, or 1.4 gm/kg mannitol infusion. The primary outcome… read more here.
Keywords: mannitol; edema; brain; brain relaxation ... See more keywords