Calcium rises induced by AMPA and nicotine receptors in the ventral tegmental area show differences in mouse brain slices prenatally exposed to nicotine
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22607
Abstract: Nicotine exposure during gestation is associated with a higher risk of adverse behavioral outcomes including a heightened liability for dependency to drugs of abuse, which can exhibit drug‐specificity influenced by gender. This enhanced liability suggests… read more here.
Keywords: exposed nicotine; tegmental area; ventral tegmental; brain slices ... See more keywords
A novel multisite confocal system for rapid Ca2+ imaging from submicron structures in brain slices.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biophotonics"
DOI: 10.1002/jbio.201700197
Abstract: In brain slices, resolving fast Ca2+ fluorescence signals from submicron structures is typically achieved using 2-photon or confocal scanning microscopy, an approach that limits the number of scanned points. The novel multiplexing confocal system presented… read more here.
Keywords: system; brain slices; ca2; submicron structures ... See more keywords
Perfusion system for studying dynamic metabolomics in rat brain slices exposed to oxygen–glucose deprivation using proton and phosphorus nuclear magnetic resonance
Sign Up to like & getrecommendations! Published in 2022 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4703
Abstract: The aim of the current study was to establish a controlled and reproducible model to study metabolic changes during oxygen–glucose deprivation (OGD) in rat brain using a nuclear magnetic resonance (NMR)‐compatible perfusion system. Rat brains… read more here.
Keywords: rat brain; brain slices; perfusion; perfusion system ... See more keywords
Accumulation of 3-APP in the ex vivo brain - observed by 31 P NMR.
Sign Up to like & getrecommendations! Published in 2022 at "NMR in biomedicine"
DOI: 10.1002/nbm.4721
Abstract: 3-Aminopropylphosphonate (3-APP) is known for its use as an exogenous indicator of extracellular volume and pH in 31 P NMR studies. We used 3-APP for estimating the extracellular volume in NMR studies of several ex… read more here.
Keywords: brain slices; vivo brain; app vivo; brain ... See more keywords
Imaging Native Calcium Currents in Brain Slices.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-12457-1_4
Abstract: Imaging techniques may overcome the limitations of electrode techniques to measure locally not only membrane potential changes, but also ionic currents. Here, we review a recently developed approach to image native neuronal Ca2+ currents from… read more here.
Keywords: currents brain; brain slices; ca2 current; ca2 ... See more keywords
Cephalosporin antibiotics are weak blockers of GABAa receptor-mediated synaptic transmission in rat brain slices.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.04.008
Abstract: Cephalosporins are beta-lactam antibiotics that are extensively used in medical practice and are reported to cause epileptic seizures in some patients. The primary cause of cephalosporin-induced convulsions is believed to be their ability to block… read more here.
Keywords: brain slices; ceftriaxone; gabaa receptor; synaptic transmission ... See more keywords
Nerve growth factor released from collagen scaffolds protects axotomized cholinergic neurons of the basal nucleus of Meynert in organotypic brain slices
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2017.12.003
Abstract: BACKGROUND Alzheimeŕs disease is accompanied by cell death of cholinergic neurons, resulting in cognitive impairment and memory loss. Nerve growth factor (NGF) is the most potent protein to support survival of cholinergic neurons. NEW METHOD… read more here.
Keywords: organotypic brain; cholinergic neurons; collagen scaffolds; brain slices ... See more keywords
P11.49 An electrophysiological signature of glioma infiltration in the ex vivo human brain
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz126.195
Abstract: Invading glioma cells affect the physiological function of the peritumoural cortex. This may manifest clinically as seizures. Here, we investigate the effect the invading glioma cells on the electrophysiological signalling of the peritumoral cortex using… read more here.
Keywords: glioma; grade; human brain; brain slices ... See more keywords
A new brain‐cutting device and ultraviolet resin‐mounted human brain slices as a teaching adjunct for neuroanatomy education
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Anatomy"
DOI: 10.1111/joa.13757
Abstract: Although the level of neuroscience research is rapidly developing with the introduction of new technologies, the method of neuroanatomy education remains at the traditional level and requires improvement to meet the needs of educators and… read more here.
Keywords: brain slices; brain; human brain; resin mounted ... See more keywords
Assaying activity-dependent arteriole and capillary responses in brain slices
Sign Up to like & getrecommendations! Published in 2022 at "Neurophotonics"
DOI: 10.1117/1.nph.9.3.031913
Abstract: Abstract. Significance Neurovascular coupling (NVC) is the process that increases cerebral blood flow in response to neuronal activity. NVC is orchestrated by signaling between neurons, glia, and vascular cells. Elucidating the mechanisms underlying NVC at… read more here.
Keywords: activity dependent; brain slices; assaying activity; brain ... See more keywords
Melatonin Supports the Survival of Cholinergic Neurons in Organotypic Brain Slices of the Basal Nucleus of Meynert
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacology"
DOI: 10.1159/000527887
Abstract: The nucleus basalis of Meynert (nBM) is the major source of cholinergic neurons in the basal forebrain, which require nerve growth factor (NGF) for their survival. Melatonin, a pleiotropic hormone, has been shown to exert… read more here.
Keywords: cholinergic neurons; brain slices; melatonin; survival cholinergic ... See more keywords