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Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108219
Abstract: Neuronal death and neuroinflammation play critical roles in regulating the progression of traumatic brain injury (TBI). However, associated pathogenesis has not been fully understood. Tumor necrosis factor receptor-associated factor 7 (TRAF7), as the unique noncanonical…
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Keywords:
brain specific;
mekk3;
brain;
tbi ... See more keywords
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Published in 2020 at "Trends in Neurosciences"
DOI: 10.1016/j.tins.2020.03.005
Abstract: Autism spectrum disorder (ASD) is a largely heritable, multistage prenatal disorder that impacts a child's ability to perceive and react to social information. Most ASD risk genes are expressed prenatally in many ASD-relevant brain regions…
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Keywords:
broadly expressed;
prenatal origins;
brain specific;
asd ... See more keywords
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Published in 2018 at "Translational Psychiatry"
DOI: 10.1038/s41398-018-0098-6
Abstract: Autism spectrum disorder (ASD) is a neuropsychiatric disorder with strong evidence of genetic contribution, and increased research efforts have resulted in an ever-growing list of ASD candidate genes. However, only a fraction of the hundreds…
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Keywords:
specific functional;
disorder;
spectrum disorder;
brain specific ... See more keywords
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Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-22751-7
Abstract: Lipid shuttling between neurons and glia contributes to the development, function, and stress responses of the nervous system. To understand how a neuron acquires its lipid supply from specific lipoproteins and their receptors, we perform…
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Keywords:
brain specific;
mediate neuron;
lipid shuttling;
astrocyte derived ... See more keywords
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Published in 2020 at "Neurological Research"
DOI: 10.1080/01616412.2020.1726588
Abstract: ABSTRACT Background: Historically, limited sensitivity associated with traditional immunoassay methods has prevented the use of brain-specific proteins as blood biomarkers of traumatic brain injury (TBI) during triage, as these proteins exhibit low circulating concentrations. Digital…
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Keywords:
specific proteins;
digital elisa;
brain specific;
brain ... See more keywords
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Published in 2019 at "Shock"
DOI: 10.1097/shk.0000000000001435
Abstract: Pneumonia is the leading cause of sepsis and septic shock. Patients who survive pneumonia are vulnerable to long-term complications including increased risk of neurocognitive dysfunction. This study investigated the immune response and long-term complications of…
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Keywords:
brain specific;
murine pneumosepsis;
model;
pneumosepsis ... See more keywords
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Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.00306
Abstract: An important function of aromatase in the brain is conversion of testosterone secreted from the testis into estradiol. Estradiol produced in the brain is thought to be deeply involved in the formation of sexually dimorphic…
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Keywords:
aro aii;
brain specific;
brain;
aromatase ... See more keywords
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Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00262
Abstract: FeatSNP is an online tool and a curated database for exploring 81 million common SNPs’ potential functional impact on the human brain. FeatSNP uses the brain transcriptomes of the human population to improve functional annotation…
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Keywords:
annotation human;
specific epigenetic;
brain specific;
database ... See more keywords