Simultaneous voxel‐wise analysis of brain and spinal cord morphometry and microstructure within the SPM framework
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25218
Abstract: To validate a simultaneous analysis tool for the brain and cervical cord embedded in the statistical parametric mapping (SPM) framework, we compared trauma‐induced macro‐ and microstructural changes in spinal cord injury (SCI) patients to controls.… read more here.
Keywords: framework; cord; analysis; brain spinal ... See more keywords
Engineering new neurons: in vivo reprogramming in mammalian brain and spinal cord
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2729-2
Abstract: Neurons are postmitotic. Once lost because of injury or degeneration, they do not regenerate in most regions of the mammalian central nervous system. Recent advancements nevertheless clearly reveal that new neurons can be reprogrammed from… read more here.
Keywords: mammalian brain; brain spinal; new neurons; spinal cord ... See more keywords
Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1207-5
Abstract: It is important to understand the molecular mechanisms of barrier disruption in the central nervous system (CNS) of patients with multiple sclerosis (MS). The purpose of the present study was to clarify whether claudin-11 is… read more here.
Keywords: claudin; brain spinal; multiple sclerosis; brain ... See more keywords
Role of Circular Ribonucleic Acids in the Treatment of Traumatic Brain and Spinal Cord Injury
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-02027-9
Abstract: The causal and pathogenetic factors linked to traumatic brain injury (TBI) and spinal cord injury (SCI) are complex. This complexity is a contributive factor in the minimal improvement outcomes of injured individuals. Several studies have… read more here.
Keywords: brain spinal; injury; circular rnas; spinal cord ... See more keywords
Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110423
Abstract: Brain and spinal cord oligodendroglia have distinct functional characteristics, and cell-autonomous loss of individual genes can result in different regional phenotypes. However, a molecular basis for these distinctions is unknown. Using single-cell analysis of oligodendroglia… read more here.
Keywords: cholesterol biosynthesis; brain; spinal cord; brain spinal ... See more keywords
Isolation, culture, and downstream characterization of primary microglia and astrocytes from adult rodent brain and spinal cord
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2020.108742
Abstract: BACKGROUND Neuroimmunologists aspire to understand the interactions between neurons, microglia, and astrocytes in the CNS. To study these cells, researchers work with either immortalized cell lines or primary cells acquired from animal tissue. Primary cells… read more here.
Keywords: brain spinal; microglia astrocytes; microglia; spinal cord ... See more keywords
Neuroprotective Effect of Syringic Acid by Modulation of Oxidative Stress and Mitochondrial Mass in Diabetic Rats
Sign Up to like & getrecommendations! Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/8297984
Abstract: Diabetes is a metabolic complaint associated with oxidative stress and dysfunction of mitochondria. One of the most common complications of diabetes mellitus is neuropathy. This study evaluated the possible neuroprotective effects of syringic acid (SYR),… read more here.
Keywords: 100 syr; brain spinal; syringic acid; diabetic rats ... See more keywords
Review of the Recent Changes in the WHO Classification for Pediatric Brain and Spinal Cord Tumors.
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric neurosurgery"
DOI: 10.1159/000528957
Abstract: BACKGROUND Periodic updates to the World Health Organization (WHO) classification system for central nervous system (CNS) tumors reflect advances in the pathological diagnosis, categorization, and molecular underpinnings of primary brain, spinal cord, and peripheral nerve… read more here.
Keywords: brain spinal; pediatric brain; classification; brain ... See more keywords
Toxicologic Pathology Forum Opinion: Interpretation of Gliosis in the Brain and Spinal Cord Observed During Nonclinical Safety Studies.
Sign Up to like & getrecommendations! Published in 2023 at "Toxicologic pathology"
DOI: 10.1177/01926233231164557
Abstract: Gliosis, defined as a nonneoplastic reaction (hypertrophy and/or proliferation) of astrocytes and/or microglial cells, is a frequent finding in the central nervous system (CNS [brain and/or spinal cord]) in nonclinical safety studies. Gliosis in rodents… read more here.
Keywords: brain spinal; nonclinical safety; safety studies; pathology ... See more keywords
Protecting the brain and spinal cord in aortic arch surgery.
Sign Up to like & getrecommendations! Published in 2018 at "Annals of cardiothoracic surgery"
DOI: 10.21037/acs.2018.05.01
Abstract: Protection of the central nervous system-either the brain or the spinal cord-during aortic surgery has been the subject of intense research over the past several decades. While it took some 30 years to prove that… read more here.
Keywords: surgery; cord; spinal cord; brain spinal ... See more keywords
Interferons in Traumatic Brain and Spinal Cord Injury: Current Evidence for Translational Application
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2018.00458
Abstract: This review article provides a general perspective of the experimental and clinical work surrounding the role of type-I, type-II, and type-III interferons (IFNs) in the pathophysiology of brain and spinal cord injury. Since IFNs are… read more here.
Keywords: brain spinal; brain; cord injury; spinal cord ... See more keywords