Recessive PRDM13 mutations cause fatal perinatal brainstem dysfunction with cerebellar hypoplasia and disrupt Purkinje cells differentiation.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2022.03.010
Abstract: Pontocerebellar hypoplasias (PCHs) are congenital disorders characterized by hypoplasia or early atrophy of the cerebellum and brainstem, leading to a very limited motor and cognitive development. Although over 20 genes have been shown to be… read more here.
Keywords: purkinje; hypoplasia; purkinje cells; brainstem dysfunction ... See more keywords
Persistent Brainstem Dysfunction in Long-COVID: A Hypothesis
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DOI: 10.1021/acschemneuro.0c00793
Abstract: Long-COVID is a postviral illness that can affect survivors of COVID-19, regardless of initial disease severity or age. Symptoms of long-COVID include fatigue, dyspnea, gastrointestinal and cardiac problems, cognitive impairments, myalgia, and others. While the… read more here.
Keywords: persistent brainstem; long covid; brainstem; hypothesis ... See more keywords
Effectiveness of Brainstem Auditory Evoked Potentials Scoring in Evaluating Brainstem Dysfunction and Disability Among Individuals With Multiple Sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of audiology"
DOI: 10.1044/2020_aja-20-00155
Abstract: Purpose The brainstem dysfunction in multiple sclerosis (MS) often causes significant functional impairment leading to disability. This study aims to explore modified brainstem auditory evoked potential (BAEP) scores based on the pattern of BAEP abnormalities… read more here.
Keywords: brainstem; disability; multiple sclerosis; baep scores ... See more keywords
Brainstem dysfunction in critically ill patients
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DOI: 10.1186/s13054-019-2718-9
Abstract: The brainstem conveys sensory and motor inputs between the spinal cord and the brain, and contains nuclei of the cranial nerves. It controls the sleep-wake cycle and vital functions via the ascending reticular activating system… read more here.
Keywords: dysfunction; ill patients; critically ill; dysfunction critically ... See more keywords
The Impact of Hyponatremia on the Severity of Childhood Tuberculous Meningitis
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DOI: 10.3389/fneur.2021.703352
Abstract: Introduction: Hyponatremia and/or hypoglycorrhachia are commonly encountered biochemical derangements during the acute stage of childhood tuberculous meningitis (TBM). Few studies have explored the correlation between these derangements and the staging of TBM disease (severity), or… read more here.
Keywords: hyponatremia; childhood tuberculous; severe hyponatremia; tuberculous meningitis ... See more keywords