Articles with "brake modulates" as a keyword



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A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration

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Published in 2022 at "Protein & Cell"

DOI: 10.1093/procel/pwac008

Abstract: Emerging evidence suggests that intron-detaining transcripts (IDTs) are a nucleus-detained and polyadenylated mRNA pool for cell to quickly and effectively respond to environmental stimuli and stress. However, the underlying mechanisms of detained intron (DI) splicing… read more here.

Keywords: contributes neurodegeneration; rnps1; molecular brake; spliceosome pausing ... See more keywords