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Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2018.12.015
Abstract: Cyclic peptides (CPs) are a promising class of molecules for drug development, particularly as inhibitors of protein-protein interactions. Predicting low-energy structures and global structural ensembles of individual CPs is critical for the design of bioactive…
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Keywords:
cyclic hexapeptides;
amino acids;
well structured;
global structural ... See more keywords
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Published in 2022 at "Nutrients"
DOI: 10.3390/nu14030483
Abstract: With extended life expectancy, the older population is constantly increasing, and consequently, so too is the prevalence of age-related disorders. Sarcopenia, the pathological age-related loss of muscle mass and function; and malnutrition, the imbalance in…
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Keywords:
bench bedside;
mitochondrial dysfunction;
branched amino;
leading sarcopenia ... See more keywords