Single-Step and Highly Sensitive Imaging of Exosomal PD-L1 through Aptamer-Activated Cascade Primer Exchange Reaction-Generated Branched DNA Nanostructures.
Sign Up to like & getrecommendations! Published in 2022 at "ACS sensors"
DOI: 10.1021/acssensors.2c01614
Abstract: Exosomal PD-L1 plays a critical role in tumor progress and immunotherapy. However, accurately analyzing exosomal PD-L1 is greatly limited by the small-sized and free-floating nature of exosomes and the few proteins each exosome carries. We… read more here.
Keywords: branched dna; single step; generated branched; imaging exosomal ... See more keywords
A Self-assembled Platform Based on Branched DNA for sgRNA/Cas9/Antisense Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b09043
Abstract: Precisely assembled DNA nanostructures are promising candidates for the delivery of biomolecule-based therapeutics. Herein, we introduce a facile strategy for the construction of a branched DNA-based nanoplatform for co-delivery of gene editing (sgRNA/Cas9, targeting DNA… read more here.
Keywords: dna; delivery; sgrna cas9; branched dna ... See more keywords