PEGylation of therapeutic oligonucletides: From linear to highly branched PEG architectures
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DOI: 10.1007/s12274-018-2131-8
Abstract: PEGylation, the attachment of poly(ethylene glycol) (PEG), has been adopted to improve the pharmacokinetic properties of oligonucleotide therapeutics for nearly 30 years. Prior efforts mainly focused on the investigation of linear or slightly branched PEG… read more here.
Keywords: pegylation therapeutic; therapeutic oligonucletides; branched peg; highly branched ... See more keywords