A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6475-8_10
Abstract: The mammary gland consists of numerous tissue compartments, including mammary epithelium, an array of stromal cells, and the extracellular matrix (ECM). Bidirectional interactions between the epithelium and its surrounding stroma are essential for proper mammary… read more here.
Keywords: branching morphogenesis; mammary gland; role; gland ... See more keywords
An Organotypic 3D Assay for Primary Human Mammary Epithelial Cells that Recapitulates Branching Morphogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7021-6_9
Abstract: We have developed a three-dimensional organotypic culture system for primary human mammary epithelial cells (HMECs) in which the cells are cultured in free floating collagen type I gels. In this assay, luminal cells predominantly form… read more here.
Keywords: epithelial cells; mammary epithelial; branching morphogenesis; human mammary ... See more keywords
Un(MaSC)ing Stem Cell Dynamics in Mammary Branching Morphogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.02.014
Abstract: The properties of stem cells that participate in mammary gland branching morphogenesis remain contested. Reporting in Nature, Scheele et al. (2017) establish a model for post-pubertal mammary branching morphogenesis in which position-dependent, lineage-restricted stem cells undergo… read more here.
Keywords: masc ing; mammary branching; branching morphogenesis; morphogenesis ... See more keywords
Whole-Mount Adult Ear Skin Imaging Reveals Defective Neuro-Vascular Branching Morphogenesis in Obese and Type 2 Diabetic Mouse Models
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18581-7
Abstract: Obesity and type 2 diabetes are frequently associated with peripheral neuropathy. Though there are multiple methods for diagnosis and analysis of morphological changes of peripheral nerves and blood vessels, three-dimensional high-resolution imaging is necessary to… read more here.
Keywords: ear skin; branching morphogenesis; whole mount; mouse ... See more keywords
Lineage tracing reveals the dynamic contribution of Id2+ progenitor cells to branching morphogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells and development"
DOI: 10.1089/scd.2021.0135
Abstract: Branching morphogenesis is an important process in shaping the arborized structures of several organs. However, the driving force that directs this process from progenitor pools remains incompletely understood. In this lineage tracing study, we investigated… read more here.
Keywords: id2; cells branching; progenitor; branching morphogenesis ... See more keywords
Abstract 5184: N-CoR2 epigenetically regulates adhesion-dependent branching morphogenesis and its loss correlates with malignant progression of the mammary gland
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs18-5184
Abstract: Branching morphogenesis depends upon extracellular matrix remodeling and dynamic cell-cell and cell-extracellular matrix interactions, although how this developmental program is coordinated remains unclear. Expression profiling of mammary tissue at different stages of branching morphogenesis combined… read more here.
Keywords: branching morphogenesis; adhesion; mammary gland; cor2 ... See more keywords
MiR-154 controls branching morphogenesis and alveologenesis in lung development involving Tgf-β signaling
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.oa3229
Abstract: Background: MiR-154 is abundant in neonatal lungs. Experimental evidence for a direct effect of miR-154 on lung development is still lacking. Aims and methods: We aim to investigate the effect of miR-154 by using an… read more here.
Keywords: morphogenesis alveologenesis; branching morphogenesis; mir 154; lung development ... See more keywords
Organ-Specific Branching Morphogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.671402
Abstract: A common developmental process, called branching morphogenesis, generates the epithelial trees in a variety of organs, including the lungs, kidneys, and glands. How branching morphogenesis can create epithelial architectures of very different shapes and functions… read more here.
Keywords: specific branching; organ specific; branching morphogenesis; morphogenesis ... See more keywords
Mathematical Approaches of Branching Morphogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00673
Abstract: Many organs require a high surface to volume ratio to properly function. Lungs and kidneys, for example, achieve this by creating highly branched tubular structures during a developmental process called branching morphogenesis. The genes that… read more here.
Keywords: kidney branching; branching morphogenesis; morphogenesis; mathematical approaches ... See more keywords
A Mammary Organoid Model to Study Branching Morphogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.826107
Abstract: Branching morphogenesis is the process that gives rise to branched structures in several organs, such as the lung, the kidney, and the mammary gland. Although morphologically well described, the exact mechanisms driving branch elongation and… read more here.
Keywords: mammary organoid; mammary gland; branching morphogenesis;
Bim Expression Modulates Branching Morphogenesis of the Epithelium and Endothelium
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12091295
Abstract: Branching morphogenesis is a key developmental process during organogenesis, such that its disruption frequently leads to long-term consequences. The kidney and eye share many etiologies, perhaps, due to similar use of developmental branching morphogenesis and… read more here.
Keywords: branching morphogenesis; ureteric bud; bim expression;